Gene Symbol |
IL3
|
Entrez Gene |
3562
|
Alt Symbol |
IL-3, MCGF, MULTI-CSF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
interleukin 3
|
Other Description |
P-cell stimulating factor|P-cell-stimulating factor|colony-stimulating factor, multiple|hematopoietic growth factor|interleukin-3|mast cell growth factor|mast-cell growth factor|multilineage-colony-stimulating factor|multipotential colony-stimulating factor
|
Swissprots |
P08700 Q6GS87
|
Accessions |
AAC08706 AAK38378 AAO88167 CBX47569 EAW62354 P08700 BC066272 AAH66272 BC066273 AAH66273 BC066274 AAH66274 BC066275 AAH66275 BC066276 AAH66276 BC069472 AAH69472 HQ448457 ADQ32937 M14743 AAA59146 M17115 AAA35725 M20137 AAA59147 NM_000588 NP_000579
|
Function |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Activated T-cells, mast cells, natural killer cells.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Apoptosis, Jak-STAT signaling pathway, Hematopoietic cell lineage, Fc epsilon RI signaling pathway
|