| Gene Symbol | IL3 |
|---|---|
| Entrez Gene | 3562 |
| Alt Symbol | IL-3, MCGF, MULTI-CSF |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 3 |
| Other Description | P-cell stimulating factor|P-cell-stimulating factor|colony-stimulating factor, multiple|hematopoietic growth factor|interleukin-3|mast cell growth factor|mast-cell growth factor|multilineage-colony-stimulating factor|multipotential colony-stimulating factor |
| Swissprots | P08700 Q6GS87 |
| Accessions | AAC08706 AAK38378 AAO88167 CBX47569 EAW62354 P08700 BC066272 AAH66272 BC066273 AAH66273 BC066274 AAH66274 BC066275 AAH66275 BC066276 AAH66276 BC069472 AAH69472 HQ448457 ADQ32937 M14743 AAA59146 M17115 AAA35725 M20137 AAA59147 NM_000588 NP_000579 |
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Activated T-cells, mast cells, natural killer cells. |
| Top Pathways | Cytokine-cytokine receptor interaction, Apoptosis, Jak-STAT signaling pathway, Hematopoietic cell lineage, Fc epsilon RI signaling pathway |
IL-3 CRISPR/Cas9 KO Plasmid (h) - sc-405253 from Santa Cruz Biotechnology
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IL-3 HDR Plasmid (h) - sc-405253-HDR from Santa Cruz Biotechnology
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IL-3 Double Nickase Plasmid (h) - sc-405253-NIC from Santa Cruz Biotechnology
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IL-3 Double Nickase Plasmid (h2) - sc-405253-NIC-2 from Santa Cruz Biotechnology
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IL-3 CRISPR Activation Plasmid (h) - sc-405253-ACT from Santa Cruz Biotechnology
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IL-3 CRISPR Activation Plasmid (h2) - sc-405253-ACT-2 from Santa Cruz Biotechnology
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IL-3 Lentiviral Activation Particles (h) - sc-405253-LAC from Santa Cruz Biotechnology
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IL-3 Lentiviral Activation Particles (h2) - sc-405253-LAC-2 from Santa Cruz Biotechnology
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IL-3 siRNA (h) - sc-39621 from Santa Cruz Biotechnology
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IL-3 shRNA Plasmid (h) - sc-39621-SH from Santa Cruz Biotechnology
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IL-3 shRNA (h) Lentiviral Particles - sc-39621-V from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ CRISPR/Cas9 KO Plasmid (h) - sc-401045 from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ HDR Plasmid (h) - sc-401045-HDR from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ Double Nickase Plasmid (h) - sc-401045-NIC from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ Double Nickase Plasmid (h2) - sc-401045-NIC-2 from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ CRISPR Activation Plasmid (h) - sc-401045-ACT from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ CRISPR Activation Plasmid (h2) - sc-401045-ACT-2 from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ Lentiviral Activation Particles (h) - sc-401045-LAC from Santa Cruz Biotechnology
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IL-3/IL-5/GM-CSFRβ Lentiviral Activation Particles (h2) - sc-401045-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10626 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10626 from Sigma-Aldrich
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IL3 siRNA (Human) - CRH2380 from Cohesion Biosciences
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IL3 - MBS828013 from MyBioSource
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shRNA set against Human IL3 (NM_000588.3) - SHH318885 from Creative biogene
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shRNA set against Human IL3(NM_000588.3) - SHL175356 from Creative biogene
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