Gene Symbol | COL18A1 |
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Entrez Gene | 80781 |
Alt Symbol | KNO, KNO1, KS |
Species | Human |
Gene Type | protein-coding |
Description | collagen, type XVIII, alpha 1 |
Other Description | antiangiogenic agent|collagen alpha-1(XVIII) chain|endostatin|multi-functional protein MFP |
Swissprots | Q96T70 Q6RZ41 Q6RZ39 Q9Y6Q7 Q8N4S4 Q58EX6 Q9UK38 Q9Y6Q8 Q8WXI5 P39060 Q6RZ40 A8MVI4 |
Accessions | AAR83296 AAR83297 AAR83298 CAB90482 CCQ43732 EAX09338 EAX09339 EAX09340 EAX09341 EAX09342 EAX09343 EAX09344 P39060 AF018081 AAC39658 AF018082 AAC39659 AF184060 AAF01310 AF333246 AF333247 AAK50626 AF416592 AAL37720 AK098216 AK130835 BC033715 AAH33715 BC063833 AAH63833 CN389577 L22548 AAA51864 NM_030582 NP_085059 NM_130444 NP_569711 NM_130445 NP_569712 |
Function | COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Present in multiple organs with highest levels in liver, lung and kidney. |
Top Pathways | Protein digestion and absorption |
COL18A1 CRISPR/Cas9 KO Plasmid (h) - sc-402281 from Santa Cruz Biotechnology
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COL18A1 HDR Plasmid (h) - sc-402281-HDR from Santa Cruz Biotechnology
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COL18A1 Double Nickase Plasmid (h) - sc-402281-NIC from Santa Cruz Biotechnology
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COL18A1 Double Nickase Plasmid (h2) - sc-402281-NIC-2 from Santa Cruz Biotechnology
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COL18A1 CRISPR Activation Plasmid (h) - sc-402281-ACT from Santa Cruz Biotechnology
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COL18A1 CRISPR Activation Plasmid (h2) - sc-402281-ACT-2 from Santa Cruz Biotechnology
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COL18A1 Lentiviral Activation Particles (h) - sc-402281-LAC from Santa Cruz Biotechnology
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COL18A1 Lentiviral Activation Particles (h2) - sc-402281-LAC-2 from Santa Cruz Biotechnology
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COL18A1 siRNA (h) - sc-43072 from Santa Cruz Biotechnology
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COL18A1 shRNA Plasmid (h) - sc-43072-SH from Santa Cruz Biotechnology
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COL18A1 shRNA (h) Lentiviral Particles - sc-43072-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU059071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6375 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6375 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09072 from Sigma-Aldrich
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COL18A1 siRNA (Human) - CRJ2915 from Cohesion Biosciences
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COL18A1 - MBS8226743 from MyBioSource
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COL18A1 CRISPR/Cas9 KO Plasmid (h2) - sc-402281-KO-2 from Santa Cruz Biotechnology
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COL18A1 HDR Plasmid (h2) - sc-402281-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human COL18A1 (NM_030582.3) - SHH267113 from Creative biogene
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shRNA set against Human COL18A1(NM_130445.2) - SHG189735 from Creative biogene
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shRNA set against Human COL18A1(NM_030582.3) - SHG189753 from Creative biogene
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COL18A1 shRNA Plasmid (Human) - CHJ2915 from Cohesion Biosciences
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COL18A1 miRNA 3'UTR clone - MiUTR1H-02307 from Creative biogene
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COL18A1 miRNA 3'UTR clone - MiUTR1H-02308 from Creative biogene
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