Gene Symbol | PIEZO2 |
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Entrez Gene | 63895 |
Alt Symbol | C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS |
Species | Human |
Gene Type | protein-coding |
Description | piezo-type mechanosensitive ion channel component 2 |
Other Description | family with sequence similarity 38, member A pseudogene|family with sequence similarity 38, member B2|piezo-type mechanosensitive ion channel component 1 pseudogene|protein PIEZO2 |
Swissprots | Q9H5R4 Q9H5I5 Q8N787 Q8NAR6 B7Z812 Q6ZS91 M4GPJ9 |
Accessions | Q9H5I5 AK026797 BAB15556 AK027056 BAB15641 AK092226 BAC03832 AK095053 AK127627 BAC87063 AK302764 BAH13798 BC148379 AAI48380 BF509086 BI829775 BM974712 CN287196 CR747105 DB319508 DV080248 DV080444 DV080488 EG327967 JN790819 AFC88283 XM_011525723 XP_011524025 XM_011525724 XP_011524026 XM_011525725 XP_011524027 XM_011525726 XP_011524028 XM_011525727 XP_011524029 NM_173817 NM_022068 NP_071351 |
Function | Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light- touch mechanosensation. {ECO:0000250|UniProtKB:Q8CD54}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
FAM38B CRISPR/Cas9 KO Plasmid (h) - sc-412957 from Santa Cruz Biotechnology
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FAM38B HDR Plasmid (h) - sc-412957-HDR from Santa Cruz Biotechnology
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FAM38B Double Nickase Plasmid (h) - sc-412957-NIC from Santa Cruz Biotechnology
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FAM38B Double Nickase Plasmid (h2) - sc-412957-NIC-2 from Santa Cruz Biotechnology
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FAM38B CRISPR Activation Plasmid (h) - sc-412957-ACT from Santa Cruz Biotechnology
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FAM38B CRISPR Activation Plasmid (h2) - sc-412957-ACT-2 from Santa Cruz Biotechnology
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FAM38B Lentiviral Activation Particles (h) - sc-412957-LAC from Santa Cruz Biotechnology
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FAM38B Lentiviral Activation Particles (h2) - sc-412957-LAC-2 from Santa Cruz Biotechnology
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FAM38B siRNA (h) - sc-77307 from Santa Cruz Biotechnology
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FAM38B shRNA Plasmid (h) - sc-77307-SH from Santa Cruz Biotechnology
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FAM38B shRNA (h) Lentiviral Particles - sc-77307-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8322 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8322 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05735 from Sigma-Aldrich
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PIEZO2 siRNA (Human) - CRJ1848 from Cohesion Biosciences
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shRNA set against Human FAM38B (NM_022068.2) - SHH291005 from Creative biogene
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Human PIEZO2 siRNA - orb272349 from Biorbyt
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PIEZO2 shRNA Plasmid (Human) - CHJ1848 from Cohesion Biosciences
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PIEZO2 miRNA 3'UTR clone - MiUTR3H-12987 from Creative biogene
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