Gene Symbol | PHF5A |
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Entrez Gene | 84844 |
Alt Symbol | INI, Rds3, SAP14b, SF3B7, SF3b14b, bK223H9.2 |
Species | Human |
Gene Type | protein-coding |
Description | PHD finger protein 5A |
Other Description | PHD finger-like domain protein 5A|PHD finger-like domain-containing protein 5A|PHD-finger 5a|splicing factor 3B associated 14 kDa protein|splicing factor 3B-associated 14 kDa protein|splicing factor 3b, subunit 7 |
Swissprots | Q7RTV0 |
Accessions | EAW60433 EAW60434 Q7RTV0 BC007321 AAH07321 BC075808 AAH75808 BK000563 DAA00074 BU584712 CR456398 CAG30284 CU012956 CAK54387 CU013244 CAK54686 EU446678 ABZ92207 NM_032758 NP_116147 |
Function | Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER- alpha. Also involved in pre-mRNA splicing. {ECO:0000269|PubMed:12234937}. |
Subcellular Location | Nucleus {ECO:0000250}. Nucleus speckle {ECO:0000250}. |
Top Pathways | Spliceosome |
PHF5A CRISPR/Cas9 KO Plasmid (h) - sc-407986 from Santa Cruz Biotechnology
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PHF5A HDR Plasmid (h) - sc-407986-HDR from Santa Cruz Biotechnology
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PHF5A Double Nickase Plasmid (h) - sc-407986-NIC from Santa Cruz Biotechnology
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PHF5A Double Nickase Plasmid (h2) - sc-407986-NIC-2 from Santa Cruz Biotechnology
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PHF5A CRISPR Activation Plasmid (h) - sc-407986-ACT from Santa Cruz Biotechnology
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PHF5A CRISPR Activation Plasmid (h2) - sc-407986-ACT-2 from Santa Cruz Biotechnology
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PHF5A Lentiviral Activation Particles (h) - sc-407986-LAC from Santa Cruz Biotechnology
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PHF5A Lentiviral Activation Particles (h2) - sc-407986-LAC-2 from Santa Cruz Biotechnology
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PHF5A siRNA (h) - sc-76119 from Santa Cruz Biotechnology
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PHF5A shRNA Plasmid (h) - sc-76119-SH from Santa Cruz Biotechnology
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PHF5A shRNA (h) Lentiviral Particles - sc-76119-V from Santa Cruz Biotechnology
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PHF5A RNAi - H00084844-R01 from Novus Biologicals
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MISSION® esiRNA - EHU016061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16732 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16732 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06221 from Sigma-Aldrich
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PHF5A siRNA (Human) - CRJ3642 from Cohesion Biosciences
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shRNA set against Human PHF5A (NM_032758.3) - SHH374800 from Creative biogene
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shRNA set against Human PHF5A(NM_032758.3) - SHR111414 from Creative biogene
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Human PHF5A siRNA - orb274143 from Biorbyt
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PHF5A shRNA Plasmid (Human) - CHJ3642 from Cohesion Biosciences
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PHF5A miRNA 3'UTR clone - MiUTR1H-07863 from Creative biogene
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