ARPP21
| Gene Symbol | ARPP21 |
|---|---|
| Entrez Gene | 10777 |
| Alt Symbol | ARPP-21, R3HDM3, RCS, TARPP |
| Species | Human |
| Gene Type | protein-coding |
| Description | cAMP-regulated phosphoprotein, 21kDa |
| Other Description | R3H domain containing 3|cAMP-regulated phosphoprotein 21|cyclic AMP-regulated phosphoprotein, 21 kD|thymocyte cAMP-regulated phosphoprotein |
| Swissprots | Q9UF93 Q9UBL0 Q6NYC3 Q4G0V4 B4DG96 Q49AK3 Q49AS6 Q86V31 |
| Accessions | AAB30130 EAW64470 EAW64471 EAW64472 Q9UBL0 AF112220 AAF17207 AK055064 BAG51459 AK091377 AK093648 AK289649 BAF82338 AK289868 BAF82557 AK294484 BAG57707 AL133109 CAB61414 AV718064 AV718166 BC017805 AAH17805 BC031106 AAH31106 BC036399 AAH36399 BC036548 BC041385 AAH41385 BC051828 AAH51828 BC066651 AAH66651 BG535216 BQ423297 BU741999 BX488342 BX537647 DA275579 EU831438 ACE87125 EU831530 ACE86449 HQ447775 ADQ32260 XM_005264811 XP_005264868 XM_006712943 XP_006713006 XM_006712944 XP_006713007 XM_006712945 XP_006713008 XM_011533298 XP_011531600 XM_011533299 XP_011531601 XM_011533300 XP_011531602 XM_011533301 XP_011531603 XM_011533302 XP_011531604 XM_011533303 XP_011531605 XM_011533304 XP_011531606 XM_011533305 XP_011531607 XM_011533306 XP_011531608 XM_011533307 XP_011531609 XM_011533308 XP_011531610 XM_011533309 XP_011531611 XM_011533310 XP_011531612 XM_011533311 XP_011531613 NM_001025068 NP_001020239 NM_001025069 NP_001020240 NM_001267616 NP_001254545 NM_001267617 NP_001254546 NM_001267618 NP_001254547 NM_001267619 NP_001254548 NM_016300 NP_057384 NM_198399 NP_938409 |
| Function | Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Tissue Specificity | Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). {ECO:0000269|PubMed:15096520, ECO:0000269|PubMed:8120638}. |
ARPP-21 CRISPR/Cas9 KO Plasmid (h) - sc-405290 from Santa Cruz Biotechnology
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ARPP-21 HDR Plasmid (h) - sc-405290-HDR from Santa Cruz Biotechnology
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ARPP-21 Double Nickase Plasmid (h) - sc-405290-NIC from Santa Cruz Biotechnology
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ARPP-21 Double Nickase Plasmid (h2) - sc-405290-NIC-2 from Santa Cruz Biotechnology
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ARPP-21 CRISPR Activation Plasmid (h) - sc-405290-ACT from Santa Cruz Biotechnology
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ARPP-21 CRISPR Activation Plasmid (h2) - sc-405290-ACT-2 from Santa Cruz Biotechnology
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ARPP-21 Lentiviral Activation Particles (h) - sc-405290-LAC from Santa Cruz Biotechnology
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ARPP-21 Lentiviral Activation Particles (h2) - sc-405290-LAC-2 from Santa Cruz Biotechnology
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ARPP-21 siRNA (h) - sc-78154 from Santa Cruz Biotechnology
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ARPP-21 shRNA Plasmid (h) - sc-78154-SH from Santa Cruz Biotechnology
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ARPP-21 shRNA (h) Lentiviral Particles - sc-78154-V from Santa Cruz Biotechnology
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ARPP-21 RNAi - H00010777-R01 from Novus Biologicals
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MISSION® esiRNA - EHU092521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3535 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3535 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10539 from Sigma-Aldrich
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ARPP21 siRNA (Human) - CRH7344 from Cohesion Biosciences
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ARPP-21 RNAi - H00010777-R03 from Novus Biologicals
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ARPP-21 RNAi - H00010777-R04 from Novus Biologicals
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ARPP-21 RNAi - H00010777-R02 from Novus Biologicals
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ARPP21 - MBS8222185 from MyBioSource
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shRNA set against Human Arpp21 (NM_198399.1) - SHH240714 from Creative biogene
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shRNA set against Human ARPP-21(NM_001025068.1) - SHG074179 from Creative biogene
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shRNA set against Human ARPP-21(NM_016300.4) - SHG074233 from Creative biogene
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Human ARPP21 siRNA - orb267846 from Biorbyt
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