Gene Symbol |
SCP2
|
Entrez Gene |
6342
|
Alt Symbol |
NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sterol carrier protein 2
|
Other Description |
non-specific lipid-transfer protein|propanoyl-CoA C-acyltransferase|sterol carrier protein X
|
Swissprots |
Q99430 D3DQ37 P22307 E1B6W5 Q6NXF4 Q15432 B4DGJ9 B4DHP6 C9JC79 Q16622 F2Z3J1 Q5VVZ1 A6NM69
|
Accessions |
AAB41286 AAD15001 CCO13809 EAX06760 EAX06761 EAX06762 P22307 AA664009 AB208789 BAD92026 AK294631 BAG57810 AK295214 BAG58208 AK303400 BAG64455 AK308105 AK312856 BAG35708 BC005911 AAH05911 BC067108 AAH67108 BG028932 BG432929 BX537618 BX537619 CA867670 DB459183 DC330171 HQ448119 ADQ32600 M55421 AAA03559 M75883 AAA03557 M75884 AAA03558 S52450 AAB24921 XM_005271103 XP_005271160 XM_011541935 XP_011540237 NM_001007098 NP_001007099 NM_001007099 NP_001007100 NM_001007100 NP_001007101 NM_001007250 NP_001007251 NM_001193599 NP_001180528 NM_001193600 NP_001180529 NM_001193617 NP_001180546 NM_002979 NP_002970
|
Function |
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis. {ECO:0000269|PubMed:17157249, ECO:0000269|PubMed:8300590}.
|
Subcellular Location |
Isoform SCP2: Mitochondrion {ECO:0000305}.
|
Tissue Specificity |
Liver, fibroblasts, and placenta.
|
Top Pathways |
Primary bile acid biosynthesis, PPAR signaling pathway, Peroxisome
|