Gene Symbol | ventx3.2 |
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Entrez Gene | 398140 |
Alt Symbol | vex1, xvex-1 |
Species | Xenopus |
Gene Type | protein-coding |
Description | VENT homeobox 3, gene 2 |
Other Description | homeobox protein vex1|homeodomain transcription factor Xvex-1|homeodomain transcription factor vex-1|ventral homeobox 1|ventral homeobox protein|vex1 |
Swissprots | Q9W769 |
Accessions | Q9W769 AF149307 AAD42079 BC170131 AAI70131 NM_001088485 NP_001081954 |
Function | Transcriptional repressor. Acts in a ventral signaling pathway downstream of bmp4 to antagonize the Spemann organizer and ventrally pattern the embryonic mesoderm. Represses transcription of the dorsal genes gsc and otx2. {ECO:0000269|PubMed:10446269, ECO:0000269|PubMed:10585564}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Widely expressed in the embryo prior to gastrulation. Becomes restricted to the ventral marginal zone by mid/late gastrulation. Ventral localization persists during gastrulation and neurulation in the ventral region of the closed blastopore and in the proctodeum during tail bud stages. {ECO:0000269|PubMed:10446269}. |
Recombinant Xenopus laevis Homeobox protein vex1(vex1) - CSB-YP894790XBE CSB-EP894790XBE CSB-BP894790XBE CSB-MP894790XBE from Cusabio
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Homeobox protein vex1 (vex1), Recombinant Protein - MBS1358728 from MyBioSource
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