Gene Symbol | NEFH |
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Entrez Gene | 4744 |
Alt Symbol | NFH |
Species | Human |
Gene Type | protein-coding |
Description | neurofilament, heavy polypeptide |
Other Description | 200 kDa neurofilament protein|NF-H|neurofilament heavy polypeptide|neurofilament triplet H protein|neurofilament, heavy polypeptide 200kDa |
Swissprots | Q9UQ14 Q9UJS7 Q96HF8 B4DYY4 P12036 |
Accessions | CAA33366 EAW59804 EAW59805 EAW59806 P12036 AA908662 AB020652 BAA74868 AF203032 AAF13722 AK302660 BAG63896 BC008648 AAH08648 BC073969 AAH73969 BE223015 BE782873 BG470629 BM686053 S66488 AAB28609 XM_011530200 XP_011528502 NM_021076 NP_066554 |
Function | Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. |
Top Pathways | Amyotrophic lateral sclerosis (ALS) |
NF-H CRISPR/Cas9 KO Plasmid (h) - sc-401267 from Santa Cruz Biotechnology
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NF-H HDR Plasmid (h) - sc-401267-HDR from Santa Cruz Biotechnology
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NF-H Double Nickase Plasmid (h) - sc-401267-NIC from Santa Cruz Biotechnology
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NF-H Double Nickase Plasmid (h2) - sc-401267-NIC-2 from Santa Cruz Biotechnology
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NF-H CRISPR Activation Plasmid (h) - sc-401267-ACT from Santa Cruz Biotechnology
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NF-H CRISPR Activation Plasmid (h2) - sc-401267-ACT-2 from Santa Cruz Biotechnology
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NF-H Lentiviral Activation Particles (h) - sc-401267-LAC from Santa Cruz Biotechnology
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NF-H Lentiviral Activation Particles (h2) - sc-401267-LAC-2 from Santa Cruz Biotechnology
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NF-H siRNA (h) - sc-42068 from Santa Cruz Biotechnology
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NF-H shRNA Plasmid (h) - sc-42068-SH from Santa Cruz Biotechnology
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NF-H shRNA (h) Lentiviral Particles - sc-42068-V from Santa Cruz Biotechnology
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NF-H RNAi - H00004744-R01 from Novus Biologicals
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MISSION® esiRNA - EHU060611 from Sigma-Aldrich
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MISSION® esiRNA - EHU102471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15191 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05262 from Sigma-Aldrich
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NEFH siRNA (Human) - CRH3150 from Cohesion Biosciences
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shRNA set against Human NEFH (NM_021076.3) - SHH351112 from Creative biogene
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NEFH shRNA Plasmid (Human) - CHH3150 from Cohesion Biosciences
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NEFH miRNA 3'UTR clone - MiUTR3H-01525 from Creative biogene
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