Gene Symbol | KIAA1804 |
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Entrez Gene | 84451 |
Alt Symbol | MLK4, dJ862P8.3 |
Species | Human |
Gene Type | protein-coding |
Description | mixed lineage kinase 4 |
Other Description | MLK4|mitogen-activated protein kinase kinase kinase MLK4 |
Swissprots | Q5TCX9 Q5TCX7 Q8WWN1 B2RN34 Q96JM1 Q8WWN2 Q5TCX8 |
Accessions | EAW69987 EAW69988 Q5TCX8 AB058707 BAB47433 AJ311797 CAC84639 AJ311798 CAC84640 AK309811 BC136648 AAI36649 BC136649 AAI36650 XM_011544305 XP_011542607 NM_032435 NP_115811 |
Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. {ECO:0000269|PubMed:21602844}. |
MLK4 CRISPR/Cas9 KO Plasmid (h) - sc-405976 from Santa Cruz Biotechnology
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MLK4 HDR Plasmid (h) - sc-405976-HDR from Santa Cruz Biotechnology
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MLK4 Double Nickase Plasmid (h) - sc-405976-NIC from Santa Cruz Biotechnology
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MLK4 Double Nickase Plasmid (h2) - sc-405976-NIC-2 from Santa Cruz Biotechnology
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MLK4 CRISPR Activation Plasmid (h) - sc-405976-ACT from Santa Cruz Biotechnology
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MLK4 CRISPR Activation Plasmid (h2) - sc-405976-ACT-2 from Santa Cruz Biotechnology
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MLK4 Lentiviral Activation Particles (h) - sc-405976-LAC from Santa Cruz Biotechnology
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MLK4 Lentiviral Activation Particles (h2) - sc-405976-LAC-2 from Santa Cruz Biotechnology
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MLK4 siRNA (h) - sc-61061 from Santa Cruz Biotechnology
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MLK4 shRNA Plasmid (h) - sc-61061-SH from Santa Cruz Biotechnology
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MLK4 shRNA (h) Lentiviral Particles - sc-61061-V from Santa Cruz Biotechnology
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MLK4 RNAi - H00084451-R02 from Novus Biologicals
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MISSION® esiRNA - EHU005501 from Sigma-Aldrich
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MISSION® siRNA - SIHK1029 from Sigma-Aldrich
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MISSION® siRNA - SIHK1028 from Sigma-Aldrich
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MISSION® siRNA - SIHK1027 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11158 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11158 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11485 from Sigma-Aldrich
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MLK4 siRNA (Human) - CRJ3483 from Cohesion Biosciences
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shRNA set against Human KIAA1804 (NM_032435.2) - SHH324883 from Creative biogene
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Human MLK4 siRNA - orb273984 from Biorbyt
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MLK4 shRNA Plasmid (Human) - CHJ3483 from Cohesion Biosciences
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KIAA1804 miRNA 3'UTR clone - MiUTR1H-05291 from Creative biogene
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