Gene Symbol | Slc7a9 |
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Entrez Gene | 30962 |
Alt Symbol | CSNU3 |
Species | Mouse |
Gene Type | protein-coding |
Description | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 |
Other Description | B(0,+)-type amino acid transporter 1|b(0,+)AT|b<o>, + amino acid transporter|b<o>, +AT|glycoprotein-associated amino acid transporter b0,+AT1|glycoprotein-associated amino acid transporter b0,+AT1|solute carrier family 7 member 9 |
Swissprots | Q9QXA6 |
Accessions | EDL03015 EDL03016 Q9QXA6 AA104782 AF192310 AAG28396 AJ249198 CAB54042 AK142541 BAE25099 AK164714 BC010746 AAH10746 BE136295 XM_006540044 XP_006540107 XM_006540045 XP_006540108 XM_006540046 XP_006540109 XM_006540047 XP_006540110 XM_011250591 XP_011248893 XM_011250592 XP_011248894 NM_001199015 NP_001185944 NM_001199016 NP_001185945 NM_021291 NP_067266 |
Function | Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney proximal tubule. {ECO:0000269|PubMed:10588648}. |
Subcellular Location | Apical cell membrane {ECO:0000305|PubMed:12167606}; Multi-pass membrane protein {ECO:0000305|PubMed:12167606}. |
Tissue Specificity | Expressed in the brush border membrane in the kidney (at protein level). {ECO:0000269|PubMed:12167606}. |
Top Pathways | Protein digestion and absorption |
SLC7A9 CRISPR/Cas9 KO Plasmid (m) - sc-424441 from Santa Cruz Biotechnology
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SLC7A9 HDR Plasmid (m) - sc-424441-HDR from Santa Cruz Biotechnology
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SLC7A9 Double Nickase Plasmid (m) - sc-424441-NIC from Santa Cruz Biotechnology
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SLC7A9 Double Nickase Plasmid (m2) - sc-424441-NIC-2 from Santa Cruz Biotechnology
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SLC7A9 CRISPR Activation Plasmid (m) - sc-424441-ACT from Santa Cruz Biotechnology
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SLC7A9 CRISPR Activation Plasmid (m2) - sc-424441-ACT-2 from Santa Cruz Biotechnology
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SLC7A9 Lentiviral Activation Particles (m) - sc-424441-LAC from Santa Cruz Biotechnology
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SLC7A9 Lentiviral Activation Particles (m2) - sc-424441-LAC-2 from Santa Cruz Biotechnology
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SLC7A9 siRNA (m) - sc-153583 from Santa Cruz Biotechnology
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SLC7A9 shRNA Plasmid (m) - sc-153583-SH from Santa Cruz Biotechnology
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SLC7A9 shRNA (m) Lentiviral Particles - sc-153583-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU013131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN41575 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41575 from Sigma-Aldrich
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SLC7A9 siRNA (Mouse) - CRM5097 from Cohesion Biosciences
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SLC7A9 - MBS8224655 from MyBioSource
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shRNA set against Mouse SLC7A9 (NM_021291.3) - SHH412212 from Creative biogene
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Mouse SLC7A9 siRNA - orb284573 from Biorbyt
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SLC7A9 shRNA Plasmid (Mouse) - CHM5097 from Cohesion Biosciences
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