Gene Symbol |
ACY1
|
Entrez Gene |
95
|
Alt Symbol |
ACY-1, ACY1D, HEL-S-5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
aminoacylase 1
|
Other Description |
N-acyl-L-amino-acid amidohydrolase|acylase|aminoacylase-1|epididymis secretory protein Li 5
|
Swissprots |
C9JWD4 C9J9D8 C9J6I6 Q03154
|
Accessions |
EAW65181 Q03154 AK298274 BAG60535 BC000545 AAH00545 BC003023 AAH03023 BC014112 AAH14112 BE269642 CD014023 CD014026 CD014027 D14524 BAA03397 D16307 BAA03814 DQ891908 ABM82834 DQ896834 ABM87833 EU794586 ACJ13640 L07548 AAA02852 NM_000666 NP_000657 NM_001198895 NP_001185824 NM_001198896 NP_001185825 NM_001198897 NP_001185826 NM_001198898 NP_001185827
|
Function |
Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). {ECO:0000269|PubMed:12933810}.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Expression is highest in kidney, strong in brain and weaker in placenta and spleen. {ECO:0000269|PubMed:16465618}.
|
Top Pathways |
Arginine and proline metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism
|