Gene Symbol | ACY1 |
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Entrez Gene | 95 |
Alt Symbol | ACY-1, ACY1D, HEL-S-5 |
Species | Human |
Gene Type | protein-coding |
Description | aminoacylase 1 |
Other Description | N-acyl-L-amino-acid amidohydrolase|acylase|aminoacylase-1|epididymis secretory protein Li 5 |
Swissprots | C9JWD4 C9J9D8 C9J6I6 Q03154 |
Accessions | EAW65181 Q03154 AK298274 BAG60535 BC000545 AAH00545 BC003023 AAH03023 BC014112 AAH14112 BE269642 CD014023 CD014026 CD014027 D14524 BAA03397 D16307 BAA03814 DQ891908 ABM82834 DQ896834 ABM87833 EU794586 ACJ13640 L07548 AAA02852 NM_000666 NP_000657 NM_001198895 NP_001185824 NM_001198896 NP_001185825 NM_001198897 NP_001185826 NM_001198898 NP_001185827 |
Function | Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). {ECO:0000269|PubMed:12933810}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expression is highest in kidney, strong in brain and weaker in placenta and spleen. {ECO:0000269|PubMed:16465618}. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism |
Aminoacylase-1 CRISPR/Cas9 KO Plasmid (h) - sc-408464 from Santa Cruz Biotechnology
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Aminoacylase-1 HDR Plasmid (h) - sc-408464-HDR from Santa Cruz Biotechnology
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Aminoacylase-1 Double Nickase Plasmid (h) - sc-408464-NIC from Santa Cruz Biotechnology
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Aminoacylase-1 Double Nickase Plasmid (h2) - sc-408464-NIC-2 from Santa Cruz Biotechnology
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Aminoacylase-1 CRISPR Activation Plasmid (h) - sc-408464-ACT from Santa Cruz Biotechnology
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Aminoacylase-1 CRISPR Activation Plasmid (h2) - sc-408464-ACT-2 from Santa Cruz Biotechnology
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Aminoacylase-1 Lentiviral Activation Particles (h) - sc-408464-LAC from Santa Cruz Biotechnology
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Aminoacylase-1 Lentiviral Activation Particles (h2) - sc-408464-LAC-2 from Santa Cruz Biotechnology
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Aminoacylase-1 siRNA (h) - sc-61966 from Santa Cruz Biotechnology
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Aminoacylase-1 shRNA Plasmid (h) - sc-61966-SH from Santa Cruz Biotechnology
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Aminoacylase-1 shRNA (h) Lentiviral Particles - sc-61966-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1773 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1773 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00406 from Sigma-Aldrich
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ACY1 siRNA (Human) - CRH0061 from Cohesion Biosciences
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Aminoacylase/ACY1 RNAi - H00000095-R01 from Novus Biologicals
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ACY1 - MBS8229010 from MyBioSource
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shRNA set against Human ACY1 (NM_000666.2) - SHH231286 from Creative biogene
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Human ACY1 siRNA - orb260563 from Biorbyt
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ACY1 shRNA Plasmid (Human) - CHH0061 from Cohesion Biosciences
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ACY1 miRNA 3'UTR clone - MiUTR3H-00122 from Creative biogene
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