POMT1

Gene Symbol POMT1
Entrez Gene 10585
Alt Symbol LGMD2K, MDDGA1, MDDGB1, MDDGC1, RT
Species Human
Gene Type protein-coding
Description protein-O-mannosyltransferase 1
Other Description dolichyl-phosphate-mannose--protein mannosyltransferase 1|protein O-mannosyl-transferase 1
Swissprots Q5JT01 B4DIF0 Q5JT08 Q9NX32 Q8NC91 Q9NX82 Q8TCA9 Q9UNT2 B3KQG0 Q5JT06 Q9Y6A1
Accessions AAD41246 CAF86827 EAW87974 EAW87975 EAW87976 EAW87977 EAW87978 Q9Y6A1 AB209430 BAD92667 AF095136 AAD41245 AK000475 BAA91190 AK074874 BAG52022 AK074888 BAC11269 AK094558 AK293529 BAG57011 AK295458 BAG58392 AK295561 BAG58462 AK299646 BAG61567 AK300393 BAG62126 AK300511 BAG62223 AK301486 BAG63000 AK303254 BAG64337 AK307876 AK315218 BC022877 AAH22877 BC065268 AAH65268 BF984005 DB154785 XM_005272156 XP_005272213 XM_005272158 XP_005272215 XM_005272159 XP_005272216 XM_005272162 XP_005272219 XM_006716932 XP_006716995 XM_011518140 XP_011516442 XM_011518141 XP_011516443 XM_011518142 XP_011516444 XM_011518143 XP_011516445 XM_011518144 XP_011516446 XM_011518145 XP_011516447 XM_011518146 XP_011516448 XM_011518147 XP_011516449 XR_929703 NM_001077365 NP_001070833 NM_001077366 NP_001070834 NM_001136113 NP_001129585 NM_001136114 NP_001129586 NM_007171 NP_009102
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. {ECO:0000269|PubMed:12369018, ECO:0000269|PubMed:14699049}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14699049}; Multi-pass membrane protein {ECO:0000269|PubMed:14699049}.
Tissue Specificity Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver.
Top Pathways Other types of O-glycan biosynthesis

POMT1 (G-10) - sc-390451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
POMT1 (G-10): sc-390451. Western blot analysis of POMT1 expression in non-transfected: sc-117752 (A) and human POMT1 transfected: sc-117092 (B) 293T whole cell lysates.

POMT1 (K-18) - sc-48915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
POMT1 (K-18): sc-48915. Western blot analysis of POMT1 expression in mouse testis tissue extract.

POMT1 (K-15) - sc-48914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

POMT1 (H-42) - sc-98908 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
POMT1 (H-42): sc-98908. Western blot analysis of POMT1 expression in A-10 whole cell lysate.

Anti-POMT1 antibody - ab200360 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-POMT1 antibody (ab200360) at 1/200 dilution + Human testis tissue lysate at 40 µgdeveloped using the ECL technique

Anti-POMT1 antibody - ab83558 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-POMT1 antibody (ab83558) at 1 µg/ml (in 5% skim milk/ PBS) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-POMT1 antibody - ab126216 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 antibody [EPR11680] - ab175234 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11680
All lanes : Anti-POMT1 antibody [EPR11680] (ab175234) at 1/10000 dilutionLane 1 : Human fetal heart lysateLane 2 : HepG2 lysateLane 3 : BxPC-3 lysateLane 4 : Human testis lysateLysates/proteins at 10 µg per lane.

Anti-POMT1 Antibody (aa706-735, APC) - LS-C207494 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa706-735, Biotin) - LS-C207495 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa706-735, FITC) - LS-C207496 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa648-697) - LS-C102153 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POMT1 antibody LS-C102153 Western blot of HepG2 cell lysate.

Anti-POMT1 Antibody (aa706-735, AP) - LS-C209021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa706-735, PE) - LS-C207498 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa706-735, Azide-free, HRP) - LS-C207497 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa713-743) - LS-C324196 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POMT1 Antibody (aa706-735) - LS-C163861 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
POMT1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

POMT1 Antibody - NBP1-60054 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: POMT1 Antibody [NBP1-60054] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

POMT1 Antibody - NBP2-19891 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: POMT1 Antibody [NBP2-19891] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.

POMT1 Polyclonal Antibody - bs-5952R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-POMT1 (C-TERM) antibody produced in rabbit - SAB1303575 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>POMT1 (C-term): <B>Cat. No. SAB1303575</B>: POMT1 in Human testis tissue with POMT1 antibody (C-term) at 10 μg/mL.

Anti-POMT1 antibody produced in rabbit - SAB2700422 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-POMT1: <B>Cat. No. SAB2700422</B>: Western Blot analysis of POMT1 in extracts from <B>Lanes</B><BR/>A. U87-MG using <B>Cat. No. SAB2700422</B> at a 1:1000 dilution.

POMT1 antibody - middle region (ARP44994_P050) - ARP44994_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

POMT1-Antibody-C-term - AP12380b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
POMT1 Antibody (C-term) (Cat. #AP12380b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

POMT1 Antibody - C-terminal region (OAAB08645) - OAAB08645 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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