Gene Symbol | GCSH |
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Entrez Gene | 2653 |
Alt Symbol | GCE, NKH |
Species | Human |
Gene Type | protein-coding |
Description | glycine cleavage system protein H (aminomethyl carrier) |
Other Description | glycine cleavage system H protein, mitochondrial|lipoic acid-containing protein|mitochondrial glycine cleavage system H-protein |
Swissprots | P23434 Q9H1E9 |
Accessions | AAP50260 EAW95545 EAW95546 P23434 AI656660 AK311978 BAG34917 AV696698 AY533031 AAS59848 BC000790 AAH00790 BC009065 BC020922 AAH20922 BF798008 BG708388 BT009827 AAP88829 CN283805 CN283809 CR457072 CAG33353 D00723 BAA00625 M69175 AAA36011 NM_004483 NP_004474 NR_033249 |
Function | The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). |
Subcellular Location | Mitochondrion. |
Top Pathways | Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism |
GCSH CRISPR/Cas9 KO Plasmid (h) - sc-406784 from Santa Cruz Biotechnology
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GCSH HDR Plasmid (h) - sc-406784-HDR from Santa Cruz Biotechnology
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GCSH Double Nickase Plasmid (h) - sc-406784-NIC from Santa Cruz Biotechnology
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GCSH Double Nickase Plasmid (h2) - sc-406784-NIC-2 from Santa Cruz Biotechnology
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GCSH CRISPR Activation Plasmid (h) - sc-406784-ACT from Santa Cruz Biotechnology
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GCSH CRISPR Activation Plasmid (h2) - sc-406784-ACT-2 from Santa Cruz Biotechnology
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GCSH Lentiviral Activation Particles (h) - sc-406784-LAC from Santa Cruz Biotechnology
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GCSH Lentiviral Activation Particles (h2) - sc-406784-LAC-2 from Santa Cruz Biotechnology
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GCSH siRNA (h) - sc-93301 from Santa Cruz Biotechnology
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GCSH shRNA Plasmid (h) - sc-93301-SH from Santa Cruz Biotechnology
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GCSH shRNA (h) Lentiviral Particles - sc-93301-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU104451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9202 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9202 from Sigma-Aldrich
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GCSH siRNA (Human) - CRH1769 from Cohesion Biosciences
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GCSH RNAi - H00002653-R01 from Novus Biologicals
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GCSH - MBS8207357 from MyBioSource
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shRNA set against Human GCSH (NM_004483.4) - SHH300166 from Creative biogene
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GCSH shRNA Plasmid (Human) - CHH1769 from Cohesion Biosciences
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GCSH miRNA 3'UTR clone - MiUTR3H-02473 from Creative biogene
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