Gene Symbol |
ZBED1
|
Entrez Gene |
9189
|
Alt Symbol |
ALTE, DREF, TRAMP, hDREF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zinc finger, BED-type containing 1
|
Other Description |
Ac-like transposable element|BED-type zinc finger domain-containing protein 1|DNA replication-related element binding factor|dREF homolog|zinc finger BED domain-containing protein 1
|
Swissprots |
O96006 Q96BY4
|
Accessions |
CAA76660 EAW98691 EAW98692 O96006 AB018328 BAA34505 BC015030 AAH15030 BM980254 DA625185 DQ893640 ABM84566 DQ895604 ABM86530 Y16947 CAA76545 NM_001171135 NP_001164606 NM_001171136 NP_001164607 NM_004729 NP_004720
|
Function |
Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity. {ECO:0000269|PubMed:12663651}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:12663651}. Note=In granular structures.
|
Tissue Specificity |
Ubiquitously expressed at low levels. Expression is highest in skeletal muscle, heart, spleen and placenta.
|