Gene Symbol | PKD2L2 |
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Entrez Gene | 27039 |
Alt Symbol | TRPP5 |
Species | Human |
Gene Type | protein-coding |
Description | polycystic kidney disease 2-like 2 |
Other Description | polycystic kidney disease 2-like 2 protein|polycystin-2L2|polycystin-L2 |
Swissprots | Q9NZM6 B4DXD2 A6NK98 E9PC91 Q9UNJ0 Q86YB4 E9PDG4 |
Accessions | EAW62174 EAW62175 EAW62176 Q9NZM6 AF118125 AAD46478 AF182034 AAF65622 AK301924 BAG63344 BC034619 BC038714 BC044581 AAH44581 BG719682 BG721989 XM_011543312 XP_011541614 XM_011543313 XP_011541615 XM_011543314 XP_011541616 XM_011543315 XP_011541617 XM_011543316 XP_011541618 XM_011543317 XP_011541619 XM_011543318 XP_011541620 XM_011543319 XP_011541621 XM_011543320 XP_011541622 XM_011543321 XP_011541623 XM_011543322 XP_011541624 NM_001258448 NP_001245377 NM_001258449 NP_001245378 NM_001300921 NP_001287850 NM_014386 NP_055201 |
Function | May function as a subunit of a cation channel and play a role in fertilization. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | According to PubMed:10602361, expressed only in testis. According to PubMed:10756092, expressed also in brain and kidney. Isoform 2 is found only in transformed lymphoblasts. Isoform 3 is found in all tissues tested. |
Polycystin-L2 CRISPR/Cas9 KO Plasmid (h) - sc-411949 from Santa Cruz Biotechnology
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Polycystin-L2 HDR Plasmid (h) - sc-411949-HDR from Santa Cruz Biotechnology
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Polycystin-L2 Double Nickase Plasmid (h) - sc-411949-NIC from Santa Cruz Biotechnology
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Polycystin-L2 Double Nickase Plasmid (h2) - sc-411949-NIC-2 from Santa Cruz Biotechnology
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Polycystin-L2 CRISPR Activation Plasmid (h) - sc-411949-ACT from Santa Cruz Biotechnology
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Polycystin-L2 CRISPR Activation Plasmid (h2) - sc-411949-ACT-2 from Santa Cruz Biotechnology
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Polycystin-L2 Lentiviral Activation Particles (h) - sc-411949-LAC from Santa Cruz Biotechnology
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Polycystin-L2 Lentiviral Activation Particles (h2) - sc-411949-LAC-2 from Santa Cruz Biotechnology
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Polycystin-L2 siRNA (h) - sc-91892 from Santa Cruz Biotechnology
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Polycystin-L2 shRNA Plasmid (h) - sc-91892-SH from Santa Cruz Biotechnology
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Polycystin-L2 shRNA (h) Lentiviral Particles - sc-91892-V from Santa Cruz Biotechnology
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PKD2L2 RNAi - H00027039-R01 from Novus Biologicals
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MISSION® esiRNA - EHU060481 from Sigma-Aldrich
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MISSION® siRNA - SIHK1720 from Sigma-Aldrich
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MISSION® siRNA - SIHK1722 from Sigma-Aldrich
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MISSION® siRNA - SIHK1721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16859 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16859 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02819 from Sigma-Aldrich
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PKD2L2 siRNA (Human) - CRH8936 from Cohesion Biosciences
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shRNA set against Human PKD2L2 (NM_014386.3) - SHH376412 from Creative biogene
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Human PKD2L2 siRNA - orb269438 from Biorbyt
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PKD2L2 shRNA Plasmid (Human) - CHH8936 from Cohesion Biosciences
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PKD2L2 miRNA 3'UTR clone - MiUTR4H-TG12148 from Creative biogene
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