Gene Symbol |
FCGBP
|
Entrez Gene |
8857
|
Alt Symbol |
FC(GAMMA)BP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Fc fragment of IgG binding protein
|
Other Description |
Human Fc gamma BP|IgG Fc binding protein|IgGFc-binding protein|fcgamma-binding protein antigen|fcgammaBP
|
Swissprots |
O95784 Q9Y6R7
|
Accessions |
AAD15624 AAD39266 EAW56926 Q9Y6R7 BE294466 BM781647 BQ065661 BU731683 BX113070 CD617655 D84239 BAA19526 XM_011548810 XP_011547112 XM_011548811 XP_011547113 XM_011548812 XP_011547114 NM_003890 NP_003881
|
Function |
May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa. {ECO:0000269|PubMed:9182547}.
|
Subcellular Location |
Secreted {ECO:0000305}.
|
Tissue Specificity |
Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level). {ECO:0000269|PubMed:11600203, ECO:0000269|PubMed:12208673, ECO:0000269|PubMed:9182547}.
|