Gene Symbol | CAPZA2 |
---|---|
Entrez Gene | 830 |
Alt Symbol | CAPPA2, CAPZ |
Species | Human |
Gene Type | protein-coding |
Description | capping protein (actin filament) muscle Z-line, alpha 2 |
Other Description | F-actin capping protein alpha-2 subunit|F-actin-capping protein subunit alpha-2|capZ alpha-2 |
Swissprots | B4DG50 P47755 |
Accessions | AAC60382 EAL24358 EAW83512 EAW83513 EAW83514 EAW83515 P47755 AK222989 BAD96709 AK223004 BAD96724 AK293405 BAG56912 AK294409 BAG57661 AK311406 AK314808 BAG37333 AK315915 BAH14286 BC005338 AAH05338 BC015963 BI553815 BT006735 AAP35381 BX386541 DQ655955 DQ655956 U03269 AAA88848 U03851 AAC00534 NM_006136 NP_006127 |
Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |