Gene Symbol | IMPG1 |
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Entrez Gene | 3617 |
Alt Symbol | GP147, IPM150, SPACR, VMD4 |
Species | Human |
Gene Type | protein-coding |
Description | interphotoreceptor matrix proteoglycan 1 |
Other Description | interphotoreceptor matrix proteoglycan of 150 kDa|sialoprotein associated with cones and rods |
Swissprots | O43686 O95094 Q68D53 A6NNZ6 Q9BWZ1 Q17R60 |
Accessions | AAC68835 EAW48725 EAW48726 EAW48727 Q17R60 AF047492 AAC03789 BC117450 AAI17451 BC117452 AAI17453 BU728582 CA391789 CR749572 CAH18367 DQ426878 HQ258361 ADR83115 NM_001282368 NP_001269297 NM_001563 NP_001554 |
Function | May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix. {ECO:0000269|PubMed:9813076}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Abundantly expressed in retina where it is specifically expressed by cone and rod photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina. {ECO:0000269|PubMed:10601738, ECO:0000269|PubMed:9719680, ECO:0000269|PubMed:9813076}. |
SPACR CRISPR/Cas9 KO Plasmid (h) - sc-406681 from Santa Cruz Biotechnology
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SPACR HDR Plasmid (h) - sc-406681-HDR from Santa Cruz Biotechnology
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SPACR Double Nickase Plasmid (h) - sc-406681-NIC from Santa Cruz Biotechnology
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SPACR Double Nickase Plasmid (h2) - sc-406681-NIC-2 from Santa Cruz Biotechnology
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SPACR CRISPR Activation Plasmid (h) - sc-406681-ACT from Santa Cruz Biotechnology
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SPACR CRISPR Activation Plasmid (h2) - sc-406681-ACT-2 from Santa Cruz Biotechnology
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SPACR Lentiviral Activation Particles (h) - sc-406681-LAC from Santa Cruz Biotechnology
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SPACR Lentiviral Activation Particles (h2) - sc-406681-LAC-2 from Santa Cruz Biotechnology
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SPACR siRNA (h) - sc-95466 from Santa Cruz Biotechnology
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SPACR shRNA Plasmid (h) - sc-95466-SH from Santa Cruz Biotechnology
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SPACR shRNA (h) Lentiviral Particles - sc-95466-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10661 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06313 from Sigma-Aldrich
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IMPG1 siRNA (Human) - CRH2422 from Cohesion Biosciences
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IMPG1 RNAi - H00003617-R02 from Novus Biologicals
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IMPG1 - MBS8228816 from MyBioSource
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SPACR CRISPR/Cas9 KO Plasmid (h2) - sc-406681-KO-2 from Santa Cruz Biotechnology
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SPACR HDR Plasmid (h2) - sc-406681-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human Impg1 (NM_001563.2) - SHH319373 from Creative biogene
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shRNA set against Human IMPG1(NM_001563.2) - SHL177544 from Creative biogene
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Human IMPG1 siRNA - orb262924 from Biorbyt
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IMPG1 shRNA Plasmid (Human) - CHH2422 from Cohesion Biosciences
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IMPG1 miRNA 3'UTR clone - MiUTR1H-04939 from Creative biogene
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