Gene Symbol | PMVK |
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Entrez Gene | 10654 |
Alt Symbol | HUMPMKI, PMK, PMKA, PMKASE |
Species | Human |
Gene Type | protein-coding |
Description | phosphomevalonate kinase |
Other Description | hPMK |
Swissprots | Q5TZW9 Q15126 |
Accessions | AAC60791 EAW53177 EAW53178 Q15126 AK130234 AK312803 BAG35661 BC006089 AAH06089 BC007694 AAH07694 BF221848 BQ061044 BT019976 AAV38779 CR541998 CAG46795 JF432626 ADZ15843 L77213 AAC37593 XM_011509084 XP_011507386 XM_011509085 XP_011507387 NM_006556 NP_006547 |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:10191291}. |
Tissue Specificity | Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. {ECO:0000269|PubMed:8663599}. |
Top Pathways | Terpenoid backbone biosynthesis, Peroxisome |
PMVK CRISPR/Cas9 KO Plasmid (h) - sc-408813 from Santa Cruz Biotechnology
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PMVK HDR Plasmid (h) - sc-408813-HDR from Santa Cruz Biotechnology
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PMVK Double Nickase Plasmid (h) - sc-408813-NIC from Santa Cruz Biotechnology
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PMVK Double Nickase Plasmid (h2) - sc-408813-NIC-2 from Santa Cruz Biotechnology
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PMVK CRISPR Activation Plasmid (h) - sc-408813-ACT from Santa Cruz Biotechnology
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PMVK CRISPR Activation Plasmid (h2) - sc-408813-ACT-2 from Santa Cruz Biotechnology
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PMVK Lentiviral Activation Particles (h) - sc-408813-LAC from Santa Cruz Biotechnology
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PMVK Lentiviral Activation Particles (h2) - sc-408813-LAC-2 from Santa Cruz Biotechnology
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PMVK siRNA (h) - sc-76180 from Santa Cruz Biotechnology
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PMVK shRNA Plasmid (h) - sc-76180-SH from Santa Cruz Biotechnology
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PMVK shRNA (h) Lentiviral Particles - sc-76180-V from Santa Cruz Biotechnology
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PMVK/phosphomevalonate kinase RNAi - H00010654-R02 from Novus Biologicals
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MISSION® esiRNA - EHU102151 from Sigma-Aldrich
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MISSION® esiRNA - EHU020431 from Sigma-Aldrich
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MISSION® siRNA - SIHK1763 from Sigma-Aldrich
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MISSION® siRNA - SIHK1761 from Sigma-Aldrich
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MISSION® siRNA - SIHK1762 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17042 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17042 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03555 from Sigma-Aldrich
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PMVK siRNA (Human) - CRH7262 from Cohesion Biosciences
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shRNA set against Human PMVK (NM_006556.3) - SHH378524 from Creative biogene
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shRNA set against Human PMVK(NM_006556.3) - SHR124458 from Creative biogene
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Human PMVK siRNA - orb267764 from Biorbyt
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PMVK shRNA Plasmid (Human) - CHH7262 from Cohesion Biosciences
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