| Gene Symbol |
GSTO2
|
| Entrez Gene |
119391
|
| Alt Symbol |
GSTO 2-2, bA127L20.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutathione S-transferase omega 2
|
| Other Description |
GSTO-2|MMA(V) reductase|bA127L20.1 (novel glutathione-S-transferase)|glutathione S-transferase omega 2-2|glutathione S-transferase omega-2|glutathione-S-transferase-like protein|glutathione-dependent dehydroascorbate reductase|monomethylarsonic acid reductase
|
| Swissprots |
B4DJW6 Q86WP3 Q49TW5 E7ESD6 Q5JU15 Q9H4Y5 A8K771 Q5GM70
|
| Accessions |
EAW49598 EAW49599 EAW49600 Q9H4Y5 AK094412 AK094859 AK097894 AK126230 AK291886 BAF84575 AK296266 BAG58978 AK297522 BAG59926 AK300508 BAG62221 AL831850 AY191318 AAO23573 AY209189 AAP47743 AY350731 AAR02452 BC023583 BC046194 BC056918 AAH56918 BM708208 DC341647 HQ448059 ADQ32540 XM_006717624 XP_006717687 XM_011539270 XP_011537572 XM_011539271 XP_011537573 XM_011539272 XP_011537574 XM_011539273 XP_011537575 NM_001191013 NP_001177942 NM_001191014 NP_001177943 NM_001191015 NP_001177944 NM_183239 NP_899062
|
| Function |
Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). {ECO:0000269|PubMed:15970797}.
|
| Tissue Specificity |
Expressed in a range of tissues, including the liver, kidney, skeletal muscle and prostate. Strongest expression in the testis. {ECO:0000269|PubMed:12618591}.
|
| Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|
