PNG1

Gene Symbol PNG1
Entrez Gene 835019
Alt Symbol AtPNG1, K6M13.12, K6M13_12, peptide-N-glycanase 1
Species Arabidopsis thaliana
Gene Type protein-coding
Description peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Other Description -
Swissprots Q9FGY9 Q84WJ1
Accessions AED95831 BAB10770 Q9FGY9 AK228156 BAF00112 AM745095 CAN87017 AY140065 AAM98206 BT003398 AAO30061 NM_124335 NP_199768
Function Specifically deglycosylates the denatured form of N- linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl- glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high- mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Protein processing in endoplasmic reticulum

Recombinant Arabidopsis thaliana Peptide-N(4)-(N-acetyl-beta-glucosaminyl)aspar - CSB-YP880733DOA CSB-EP880733DOA CSB-BP880733DOA CSB-MP880733DOA from Cusabio

Category Peptide
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Arabidopsis thaliana

Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1), partial, Recombinant Protein - MBS1416921 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Arabidopsis thaliana
Search more