| Gene Symbol |
CD93
|
| Entrez Gene |
22918
|
| Alt Symbol |
C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD93 molecule
|
| Other Description |
C1q receptor 1|C1q/MBL/SPA receptor|C1qR|CD93 antigen|complement component 1 q subcomponent receptor 1|complement component 1, q subcomponent, receptor 1|complement component C1q receptor|matrix-remodeling-associated protein 4|matrix-remodelling associated 4
|
| Swissprots |
O00274 Q9NPY3
|
| Accessions |
EAX10171 Q9NPY3 AB209895 BAD93132 AJ295142 CAC82720 AK056764 AK299957 BAG61784 AM393282 CAL38160 AM393752 CAL38627 BC028075 AAH28075 DQ891055 ABM81981 DQ894234 ABM85160 U94333 AAB53110 NM_012072 NP_036204
|
| Function |
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin.
|