Gene Symbol |
FAM129B
|
Entrez Gene |
64855
|
Alt Symbol |
C9orf88, MEG-3, MINERVA, OC58, bA356B19.6
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
family with sequence similarity 129, member B
|
Other Description |
melanoma invasion by ERK|niban-like protein 1
|
Swissprots |
Q5VVW6 Q4LE55 Q9BUS2 Q9NT35 Q5VVW7 Q96TA1
|
Accessions |
EAW87675 EAW87676 EAW87677 EAW87678 Q96TA1 AB210016 BAE06098 AF151783 AAK57556 AF192911 AAQ13825 AK023580 BAB14615 AK025804 BAB15240 AK025951 AL137555 CAB70809 BC001979 AAH01979 BC018849 BC023210 BC067366 BC110345 AAI10346 BE300704 BM557756 BX280720 CN423640 XM_005252135 XP_005252192 XM_011518925 XP_011517227 NM_001035534 NP_001030611 NM_022833 NP_073744
|
Function |
May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro. {ECO:0000269|PubMed:19362540, ECO:0000269|PubMed:21148485}.
|
Subcellular Location |
Cytoplasm, cytosol. Cell junction, adherens junction. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
|