| Gene Symbol |
HSPA6
|
| Entrez Gene |
3310
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heat shock 70kDa protein 6 (HSP70B')
|
| Other Description |
heat shock 70 kDa protein 6|heat shock 70 kDa protein B'|heat shock 70kD protein 6 (HSP70B')
|
| Swissprots |
Q1HBA8 P17066 Q8IYK7 Q9BT95
|
| Accessions |
ABF47108 CAA36061 P17066 AK093925 BAG52788 AK223362 BAD97082 AK295212 BAG58207 AK312756 BAG35622 BC004279 AAH04279 BC035665 AAH35665 BQ008960 BQ217460 CD366171 DQ892446 ABM83372 DQ895657 ABM86583 X51758 CAA36062 NM_002155 NP_002146
|
| Function |
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity). {ECO:0000250}.
|
| Top Pathways |
Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A, Measles
|