| Gene Symbol | CTSG |
|---|---|
| Entrez Gene | 1511 |
| Alt Symbol | CATG, CG |
| Species | Human |
| Gene Type | protein-coding |
| Description | cathepsin G |
| Other Description | - |
| Swissprots | P08311 Q9UCA5 Q6IBJ6 Q9UCU6 |
| Accessions | AAA51919 EAW66006 P08311 AI272833 AK225914 BC014460 AAH14460 CR456807 CAG33088 CR541704 CAG46505 DQ893067 ABM83993 DQ896320 ABM87319 M16117 AAA52126 XM_011536499 XP_011534801 NM_001911 NP_001902 |
| Function | Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. {ECO:0000269|PubMed:1861080, ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:8194606}. |
| Subcellular Location | Cell surface {ECO:0000269|PubMed:8194606}. |
| Top Pathways | Systemic lupus erythematosus, Lysosome, Amoebiasis, Renin-angiotensin system, Neuroactive ligand-receptor interaction |