Gene Symbol | CTSG |
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Entrez Gene | 1511 |
Alt Symbol | CATG, CG |
Species | Human |
Gene Type | protein-coding |
Description | cathepsin G |
Other Description | - |
Swissprots | P08311 Q9UCA5 Q6IBJ6 Q9UCU6 |
Accessions | AAA51919 EAW66006 P08311 AI272833 AK225914 BC014460 AAH14460 CR456807 CAG33088 CR541704 CAG46505 DQ893067 ABM83993 DQ896320 ABM87319 M16117 AAA52126 XM_011536499 XP_011534801 NM_001911 NP_001902 |
Function | Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. {ECO:0000269|PubMed:1861080, ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:8194606}. |
Subcellular Location | Cell surface {ECO:0000269|PubMed:8194606}. |
Top Pathways | Systemic lupus erythematosus, Lysosome, Amoebiasis, Renin-angiotensin system, Neuroactive ligand-receptor interaction |
cathepsin G CRISPR/Cas9 KO Plasmid (h) - sc-402663 from Santa Cruz Biotechnology
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cathepsin G HDR Plasmid (h) - sc-402663-HDR from Santa Cruz Biotechnology
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cathepsin G Double Nickase Plasmid (h) - sc-402663-NIC from Santa Cruz Biotechnology
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cathepsin G Double Nickase Plasmid (h2) - sc-402663-NIC-2 from Santa Cruz Biotechnology
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cathepsin G CRISPR Activation Plasmid (h) - sc-402663-ACT from Santa Cruz Biotechnology
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cathepsin G CRISPR Activation Plasmid (h2) - sc-402663-ACT-2 from Santa Cruz Biotechnology
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cathepsin G Lentiviral Activation Particles (h) - sc-402663-LAC from Santa Cruz Biotechnology
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cathepsin G Lentiviral Activation Particles (h2) - sc-402663-LAC-2 from Santa Cruz Biotechnology
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cathepsin G siRNA (h) - sc-41477 from Santa Cruz Biotechnology
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cathepsin G shRNA Plasmid (h) - sc-41477-SH from Santa Cruz Biotechnology
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cathepsin G shRNA (h) Lentiviral Particles - sc-41477-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU028931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6752 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6752 from Sigma-Aldrich
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CTSG siRNA (Human) - CRH1068 from Cohesion Biosciences
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CTSG - MBS8224431 from MyBioSource
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shRNA set against Human CTSG (NM_001911.2) - SHH271553 from Creative biogene
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shRNA set against Human CTSG(NM_001911.2) - SHG206745 from Creative biogene
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Human Cathepsin G siRNA - orb261570 from Biorbyt
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CTSG shRNA Plasmid (Human) - CHH1068 from Cohesion Biosciences
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CTSG miRNA 3'UTR clone - MiUTR1H-02545 from Creative biogene
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