Gene Symbol | ZNF593 |
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Entrez Gene | 51042 |
Alt Symbol | ZT86 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 593 |
Other Description | zinc finger protein T86 |
Swissprots | Q5T2H7 B2R4S0 O00488 |
Accessions | EAX07843 O00488 AI083892 AK311926 BAG34867 BC002580 AAH02580 BC019267 AAH19267 D45213 BAA20369 DA124660 EU446798 ABZ92327 U38444 NM_015871 NP_056955 |
Function | Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
Tissue Specificity | Ubiquitous. Detected in spleen, prostate, testis, small intestine, colon and to a minor level in thymus and peripheral blood leukocytes. |
ZNF593 CRISPR/Cas9 KO Plasmid (h) - sc-412098 from Santa Cruz Biotechnology
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ZNF593 HDR Plasmid (h) - sc-412098-HDR from Santa Cruz Biotechnology
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ZNF593 Double Nickase Plasmid (h) - sc-412098-NIC from Santa Cruz Biotechnology
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ZNF593 Double Nickase Plasmid (h2) - sc-412098-NIC-2 from Santa Cruz Biotechnology
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ZNF593 CRISPR Activation Plasmid (h) - sc-412098-ACT from Santa Cruz Biotechnology
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ZNF593 CRISPR Activation Plasmid (h2) - sc-412098-ACT-2 from Santa Cruz Biotechnology
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ZNF593 Lentiviral Activation Particles (h) - sc-412098-LAC from Santa Cruz Biotechnology
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ZNF593 Lentiviral Activation Particles (h2) - sc-412098-LAC-2 from Santa Cruz Biotechnology
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ZNF593 siRNA (h) - sc-78792 from Santa Cruz Biotechnology
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ZNF593 shRNA Plasmid (h) - sc-78792-SH from Santa Cruz Biotechnology
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ZNF593 shRNA (h) Lentiviral Particles - sc-78792-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23572 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23572 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00194 from Sigma-Aldrich
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ZNF593 siRNA (Human) - CRH9474 from Cohesion Biosciences
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ZNF593 RNAi - H00051042-R01 from Novus Biologicals
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ZNF593 - MBS8222199 from MyBioSource
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shRNA set against Human ZNF593 (NM_015871.4) - SHH454544 from Creative biogene
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Human ZNF593 siRNA - orb269976 from Biorbyt
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ZNF593 shRNA Plasmid (Human) - CHH9474 from Cohesion Biosciences
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ZNF593 miRNA 3'UTR clone - MiUTR1H-11660 from Creative biogene
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