| Gene Symbol |
Atp6v0d1
|
| Entrez Gene |
11972
|
| Alt Symbol |
AI267038, Ac39, Atp6d, P39, VATX, Vma6
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal V0 subunit D1
|
| Other Description |
ATPase, H+ transporting, V0 subunit D|ATPase, H+ transporting, lysosomal (vacuolar proton pump), 42 kDa|ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D|V-ATPase 40 kDa accessory protein|V-ATPase AC39 subunit|V-ATPase subunit d 1|V-type proton ATPase subunit d 1|lysosomal 38kDa|physophilin|vacuolar proton pump subunit d 1
|
| Swissprots |
Q54A57 Q9QWJ2 P51863
|
| Accessions |
EDL11286 P51863 AB088408 BAC57954 AK083372 BAC38889 AK133921 AK171515 BAE42500 AK213362 BC011075 AAH11075 U13840 AAC83085 U21549 AAA92288 NM_013477 NP_038505
|
| Function |
Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Localizes to centrosome and the base of the cilium. {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:12527205, ECO:0000269|PubMed:12963731}.
|
| Top Pathways |
Phagosome, Rheumatoid arthritis, Collecting duct acid secretion, Synaptic vesicle cycle, Lysosome
|