Gene Symbol | SPAG6 |
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Entrez Gene | 9576 |
Alt Symbol | CT141, Repro-SA-1, pf16 |
Species | Human |
Gene Type | protein-coding |
Description | sperm associated antigen 6 |
Other Description | axoneme central apparatus protein|protein PF16 homolog|sperm flagellar protein|sperm-associated antigen 6 |
Swissprots | Q5VUX5 A8K1I8 Q5VUX6 O75602 Q8NHQ6 B4DXZ4 Q6FI74 Q5VUX7 |
Accessions | ABO32592 EAW86143 EAW86144 EAW86145 EAW86146 EAW86147 O75602 AF079363 AAC32590 AK289903 BAF82592 AK302194 BAG63556 AK310247 AL080136 CAB45730 AM392674 CAL37552 AM392698 CAL37576 BC030585 AAH30585 BI561430 CR533552 CAG38583 DB025758 DB057157 DQ890916 ABM81842 DQ894067 ABM84993 HM370395 ADM86748 XM_005252645 XP_005252702 XM_005252646 XP_005252703 NM_001253854 NP_001240783 NM_001253855 NP_001240784 NM_012443 NP_036575 NM_172242 NP_758442 |
Function | Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10493827}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:10493827}. Note=Associated with microtubules. Detected on the sperm flagellum. |
Tissue Specificity | Highly expressed in testis. {ECO:0000269|PubMed:10493827}. |
SPAG6 CRISPR/Cas9 KO Plasmid (h) - sc-409744 from Santa Cruz Biotechnology
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SPAG6 HDR Plasmid (h) - sc-409744-HDR from Santa Cruz Biotechnology
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SPAG6 Double Nickase Plasmid (h) - sc-409744-NIC from Santa Cruz Biotechnology
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SPAG6 Double Nickase Plasmid (h2) - sc-409744-NIC-2 from Santa Cruz Biotechnology
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SPAG6 CRISPR Activation Plasmid (h) - sc-409744-ACT from Santa Cruz Biotechnology
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SPAG6 CRISPR Activation Plasmid (h2) - sc-409744-ACT-2 from Santa Cruz Biotechnology
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SPAG6 Lentiviral Activation Particles (h) - sc-409744-LAC from Santa Cruz Biotechnology
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SPAG6 Lentiviral Activation Particles (h2) - sc-409744-LAC-2 from Santa Cruz Biotechnology
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SPAG6 siRNA (h) - sc-90404 from Santa Cruz Biotechnology
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SPAG6 shRNA Plasmid (h) - sc-90404-SH from Santa Cruz Biotechnology
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SPAG6 shRNA (h) Lentiviral Particles - sc-90404-V from Santa Cruz Biotechnology
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SPAG6 RNAi - H00009576-R02 from Novus Biologicals
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SPAG6 RNAi - H00009576-R01 from Novus Biologicals
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MISSION® esiRNA - EHU063461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20389 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20389 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07259 from Sigma-Aldrich
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SPAG6 siRNA (Human) - CRH6371 from Cohesion Biosciences
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SPAG6 - MBS8200836 from MyBioSource
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shRNA set against Human SPAG6 (NM_012443.3) - SHH415864 from Creative biogene
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Human SPAG6 siRNA - orb266873 from Biorbyt
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SPAG6 shRNA Plasmid (Human) - CHH6371 from Cohesion Biosciences
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SPAG6 miRNA 3'UTR clone - MiUTR3H-07913 from Creative biogene
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SPAG6 miRNA 3'UTR clone - MiUTR3H-07914 from Creative biogene
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