| Gene Symbol |
HNRNPM
|
| Entrez Gene |
4670
|
| Alt Symbol |
CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP M
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heterogeneous nuclear ribonucleoprotein M
|
| Other Description |
CEA receptor|N-acetylglucosamine receptor 1|heterogenous nuclear ribonucleoprotein M4|hnRNA-binding protein M4
|
| Swissprots |
Q9BWL9 Q9Y492 Q15584 Q96H56 P52272 Q8WZ44
|
| Accessions |
EAW68919 EAW68920 EAW68921 EAW68922 EAW68923 P52272 AA244120 AB209733 BAD92970 AF061832 AAC16002 AK024911 AK309659 AL713781 CAD28541 BC000138 AAH00138 BC008895 AAH08895 BC018916 BC019580 AAH19580 BC038753 BC045573 BC054874 BC058893 BC064588 AAH64588 CN350481 CN350489 CN350526 DB478004 DB481659 HY007201 L03532 AAA36192 L32611 AAL31359 X72018 CAA50897 XM_005272478 XP_005272535 XM_005272479 XP_005272536 XM_005272480 XP_005272537 XM_005272481 XP_005272538 XM_005272483 XP_005272540 NM_001297418 NP_001284347 NM_005968 NP_005959 NM_031203 NP_112480
|
| Function |
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|Ref.5}.
|
| Top Pathways |
Spliceosome
|
![Western Blot: hnRNP M Overexpression Lysate (Adult Normal) [NBL1-11650] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for hnRNP M.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8078_hnRNP%2520M%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11650-img0002.jpg)