| Gene Symbol |
COL4A2
|
| Entrez Gene |
1284
|
| Alt Symbol |
ICH, POREN2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type IV, alpha 2
|
| Other Description |
canstatin|collagen alpha-2(IV) chain
|
| Swissprots |
P08572 Q548C3 Q66K23 Q5VZA9 Q14052
|
| Accessions |
AAA53097 AAA53099 CAA31275 EAX09111 EAX09112 P08572 AF258350 AAF72631 AF400430 AAK92479 AK025912 AK294920 BAG58004 AY450357 AAR20245 AY455978 AAR18250 BC016166 BC035559 BC068210 BC080644 AAH80644 BX648393 BY795218 CB045156 CB148713 CK000715 CN397790 CN397808 CN397819 J02760 AAA58422 M24766 AAA52043 X05562 CAA29076 X05610 CAA29098 NM_001846 NP_001837
|
| Function |
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Protein digestion and absorption
|