Gene Symbol | EYS |
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Entrez Gene | 346007 |
Alt Symbol | C6orf178, C6orf179, C6orf180, EGFL10, EGFL11, RP25, SPAM, bA166P24.2, bA307F22.3, bA74E24.1, dJ1018A4.2, dJ22I17.2, dJ303F19.1 |
Species | Human |
Gene Type | protein-coding |
Description | eyes shut homolog (Drosophila) |
Other Description | EGF-like-domain, multiple 10|EGF-like-domain, multiple 11|epidermal growth factor-like protein 10|epidermal growth factor-like protein 11|protein eyes shut homolog|protein spacemaker homolog |
Swissprots | B7ZBR3 B7ZBE7 Q6UY05 B7ZBE8 Q5T1H1 A2RUR2 B7UUQ3 Q9NQ15 Q9H557 A8MVE7 Q5T669 B9ZVD2 Q5SZM4 Q5T3C8 Q5TEL4 Q5VVG4 B7TYK8 Q5TEL3 |
Accessions | CAB99359 CCQ43113 EAW88497 Q5T1H1 AB593112 BAJ84052 AB593114 BAJ84054 AK310478 AY358133 AAQ88500 BC133011 AAI33012 BC133013 AAI33014 BX537914 BX647741 FJ416331 ACJ37365 FM209056 CAR64275 NM_001142800 NP_001136272 NM_001142801 NP_001136273 NM_001292009 NP_001278938 NM_198283 NP_938024 |
Function | Required to maintain the integrity of photoreceptor cells. {ECO:0000269|PubMed:18836446}. |
Subcellular Location | Secreted {ECO:0000305|PubMed:18836446}. Note=Localizes in the photoreceptor cell layer. |
Tissue Specificity | Present in retina. {ECO:0000269|PubMed:18836446, ECO:0000269|PubMed:18976725}. |
EGFL11 CRISPR/Cas9 KO Plasmid (h) - sc-406815 from Santa Cruz Biotechnology
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EGFL11 HDR Plasmid (h) - sc-406815-HDR from Santa Cruz Biotechnology
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EGFL11 Double Nickase Plasmid (h) - sc-406815-NIC from Santa Cruz Biotechnology
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EGFL11 Double Nickase Plasmid (h2) - sc-406815-NIC-2 from Santa Cruz Biotechnology
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EGFL11 CRISPR Activation Plasmid (h) - sc-406815-ACT from Santa Cruz Biotechnology
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EGFL11 CRISPR Activation Plasmid (h2) - sc-406815-ACT-2 from Santa Cruz Biotechnology
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EGFL11 Lentiviral Activation Particles (h) - sc-406815-LAC from Santa Cruz Biotechnology
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EGFL11 Lentiviral Activation Particles (h2) - sc-406815-LAC-2 from Santa Cruz Biotechnology
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EGFL10 siRNA (h) - sc-95342 from Santa Cruz Biotechnology
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EGFL10 shRNA Plasmid (h) - sc-95342-SH from Santa Cruz Biotechnology
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EGFL11 siRNA (h) - sc-95498 from Santa Cruz Biotechnology
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EGFL11 shRNA Plasmid (h) - sc-95498-SH from Santa Cruz Biotechnology
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EGFL11 shRNA (h) Lentiviral Particles - sc-95498-V from Santa Cruz Biotechnology
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EYS/RP25 RNAi - H00346007-R01 from Novus Biologicals
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MISSION® esiRNA - EHU042411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8065 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8065 from Sigma-Aldrich
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EYS siRNA (Human) - CRJ7477 from Cohesion Biosciences
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EYS - MBS8227186 from MyBioSource
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EGFL11 CRISPR/Cas9 KO Plasmid (h2) - sc-406815-KO-2 from Santa Cruz Biotechnology
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EGFL11 HDR Plasmid (h2) - sc-406815-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human EYS (NM_198283.1) - SHH288317 from Creative biogene
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Human EYS siRNA - orb277978 from Biorbyt
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EYS shRNA Plasmid (Human) - CHJ7477 from Cohesion Biosciences
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EYS miRNA 3'UTR clone - MiUTR1H-03135 from Creative biogene
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