| Gene Symbol | LIPT1 |
|---|---|
| Entrez Gene | 51601 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | lipoyltransferase 1 |
| Other Description | lipoate biosynthesis protein|lipoyl ligase|lipoyltransferase 1, mitochondrial |
| Swissprots | Q4ZFZ1 Q9Y234 |
| Accessions | AAX88927 BAA76368 EAX01877 Q9Y234 AA811675 AB017566 BAA76367 BC007001 AAH07001 BC009772 AAH09772 BC070145 AAH70145 BG717409 BQ422048 BQ432795 BX100979 DA607268 HQ448274 ADQ32754 NM_001204830 NP_001191759 NM_015929 NP_057013 NM_145197 NP_660198 NM_145198 NP_660199 NM_145199 NP_660200 NR_037935 NR_037936 NM_145196 |
| Function | Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes. {ECO:0000250}. |
| Subcellular Location | Mitochondrion. |
| Tissue Specificity | Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung. {ECO:0000269|PubMed:10103005}. |
| Top Pathways | Lipoic acid metabolism |