Gene Symbol | LIPT1 |
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Entrez Gene | 51601 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | lipoyltransferase 1 |
Other Description | lipoate biosynthesis protein|lipoyl ligase|lipoyltransferase 1, mitochondrial |
Swissprots | Q4ZFZ1 Q9Y234 |
Accessions | AAX88927 BAA76368 EAX01877 Q9Y234 AA811675 AB017566 BAA76367 BC007001 AAH07001 BC009772 AAH09772 BC070145 AAH70145 BG717409 BQ422048 BQ432795 BX100979 DA607268 HQ448274 ADQ32754 NM_001204830 NP_001191759 NM_015929 NP_057013 NM_145197 NP_660198 NM_145198 NP_660199 NM_145199 NP_660200 NR_037935 NR_037936 NM_145196 |
Function | Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes. {ECO:0000250}. |
Subcellular Location | Mitochondrion. |
Tissue Specificity | Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung. {ECO:0000269|PubMed:10103005}. |
Top Pathways | Lipoic acid metabolism |
LIPT1 CRISPR/Cas9 KO Plasmid (h) - sc-408883 from Santa Cruz Biotechnology
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LIPT1 HDR Plasmid (h) - sc-408883-HDR from Santa Cruz Biotechnology
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LIPT1 Double Nickase Plasmid (h) - sc-408883-NIC from Santa Cruz Biotechnology
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LIPT1 Double Nickase Plasmid (h2) - sc-408883-NIC-2 from Santa Cruz Biotechnology
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LIPT1 CRISPR Activation Plasmid (h) - sc-408883-ACT from Santa Cruz Biotechnology
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LIPT1 CRISPR Activation Plasmid (h2) - sc-408883-ACT-2 from Santa Cruz Biotechnology
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LIPT1 Lentiviral Activation Particles (h) - sc-408883-LAC from Santa Cruz Biotechnology
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LIPT1 Lentiviral Activation Particles (h2) - sc-408883-LAC-2 from Santa Cruz Biotechnology
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LIPT1 siRNA (h) - sc-94383 from Santa Cruz Biotechnology
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LIPT1 shRNA Plasmid (h) - sc-94383-SH from Santa Cruz Biotechnology
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LIPT1 shRNA (h) Lentiviral Particles - sc-94383-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU140611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11751 from Sigma-Aldrich
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LIPT1 siRNA (Human) - CRH9852 from Cohesion Biosciences
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shRNA set against Human LIPT1 (NM_015929.3) - SHH330759 from Creative biogene
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Human LIPT1 siRNA - orb270354 from Biorbyt
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LIPT1 shRNA Plasmid (Human) - CHH9852 from Cohesion Biosciences
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LIPT1 miRNA 3'UTR clone - MiUTR3H-11124 from Creative biogene
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LIPT1 miRNA 3'UTR clone - MiUTR3H-11125 from Creative biogene
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LIPT1 miRNA 3'UTR clone - MiUTR3H-11126 from Creative biogene
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LIPT1 miRNA 3'UTR clone - MiUTR3H-11127 from Creative biogene
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