| Gene Symbol |
SSH2
|
| Entrez Gene |
85464
|
| Alt Symbol |
SSH-2, SSH-2L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
slingshot protein phosphatase 2
|
| Other Description |
SSH-like protein 2|protein phosphatase Slingshot homolog 2
|
| Swissprots |
Q96H36 Q8WYL1 Q8TDB5 Q76I76 Q8WYL2 Q9C0D8 Q96F40
|
| Accessions |
CCQ43800 EAW51209 EAW51210 EAW51211 EAW51212 EAW51213 Q76I76 AB051512 BAB21816 AB072358 BAB84117 AB072359 BAB84118 AB099290 BAC97813 AF484838 AAL92027 AI609950 AK091432 BAG52360 AK094204 AK094429 AK296413 BAG59076 AK308887 BC008941 AAH08941 BC011636 AAH11636 BC068223 AAH68223 BC166670 AAI66670 DA749059 DA861985 XM_005258058 XP_005258115 XM_005258059 XP_005258116 XM_005258060 XP_005258117 XM_006722149 XP_006722212 XM_011525402 XP_011523704 XM_011525403 XP_011523705 XM_011525404 XP_011523706 XM_011525405 XP_011523707 XM_011525406 XP_011523708 XM_011525407 XP_011523709 NM_001282129 NP_001269058 NM_001282130 NP_001269059 NM_001282131 NP_001269060 NM_033389 NP_203747
|
| Function |
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. {ECO:0000269|PubMed:11832213}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton.
|
| Top Pathways |
Regulation of actin cytoskeleton
|