| Gene Symbol |
SULT1A2
|
| Entrez Gene |
6799
|
| Alt Symbol |
HAST4, P-PST, ST1A2, STP2, TSPST2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
|
| Other Description |
P-PST 2|aryl sulfotransferase 2|arylamine sulfotransferase|phenol sulfotransferase 2|phenol-preferring phenol sulfotransferase2|phenol-sulfating phenol sulfotransferase 2|phenolic-metabolizing (P) form of PST|sulfotransferase 1A2|thermostable phenol sulfotransferase
|
| Swissprots |
P78393 Q14CJ7 P50226 A9QY25
|
| Accessions |
AAB08970 AAB09758 AAB18753 AAC51149 P50226 BC025763 BC052280 BC113727 AAI13728 BC113729 AAI13730 U28169 AAB09658 U28170 AAB09659 X78282 CAA55088 XM_006721076 XP_006721139 XM_006721077 XP_006721140 XM_011545922 XP_011544224 XM_011545923 XP_011544225 XM_011545924 XP_011544226 XR_950836 NM_001054 NP_001045 NM_177528 NP_803564
|
| Function |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Chemical carcinogenesis
|