Gene Symbol | CCL17 |
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Entrez Gene | 6361 |
Alt Symbol | A-152E5.3, ABCD-2, SCYA17, TARC |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 17 |
Other Description | C-C motif chemokine 17|CC chemokine TARC|T cell-directed CC chemokine|small inducible cytokine subfamily A (Cys-Cys), member 17|small-inducible cytokine A17|thymus and activation-regulated chemokine |
Swissprots | Q92583 Q2M287 A0N0Q9 |
Accessions | AAC24308 ABK41950 BAC20219 EAW82921 Q92583 BC069107 AAH69107 BC112066 AAI12067 BC112068 AAI12069 BE061171 D43767 BAA07824 XM_011523256 XP_011521558 NM_002987 NP_002978 |
Function | Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. {ECO:0000269|PubMed:10540332}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed at high levels in thymus and at low levels in the lung, colon and small intestine. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
TARC CRISPR/Cas9 KO Plasmid (h) - sc-401905 from Santa Cruz Biotechnology
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TARC HDR Plasmid (h) - sc-401905-HDR from Santa Cruz Biotechnology
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TARC Double Nickase Plasmid (h) - sc-401905-NIC from Santa Cruz Biotechnology
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TARC Double Nickase Plasmid (h2) - sc-401905-NIC-2 from Santa Cruz Biotechnology
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TARC CRISPR Activation Plasmid (h) - sc-401905-ACT from Santa Cruz Biotechnology
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TARC CRISPR Activation Plasmid (h2) - sc-401905-ACT-2 from Santa Cruz Biotechnology
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TARC Lentiviral Activation Particles (h) - sc-401905-LAC from Santa Cruz Biotechnology
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TARC Lentiviral Activation Particles (h2) - sc-401905-LAC-2 from Santa Cruz Biotechnology
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TARC siRNA (h) - sc-39369 from Santa Cruz Biotechnology
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TARC shRNA Plasmid (h) - sc-39369-SH from Santa Cruz Biotechnology
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TARC shRNA (h) Lentiviral Particles - sc-39369-V from Santa Cruz Biotechnology
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CCL17/TARC RNAi - H00006361-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5602 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5602 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00773 from Sigma-Aldrich
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CCL17 siRNA (Human) - CRH4294 from Cohesion Biosciences
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CCL17 - MBS8238611 from MyBioSource
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shRNA set against Human CCL17 (NM_002987.2) - SHH257521 from Creative biogene
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shRNA set against Human CCL17(NM_002987.2) - SHG150557 from Creative biogene
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Human CCL17 siRNA - orb264796 from Biorbyt
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CCL17 shRNA Plasmid (Human) - CHH4294 from Cohesion Biosciences
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CCL17 miRNA 3'UTR clone - MiUTR1H-01793 from Creative biogene
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