Gene Symbol | TOR2A |
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Entrez Gene | 27433 |
Alt Symbol | TORP1 |
Species | Human |
Gene Type | protein-coding |
Description | torsin family 2, member A |
Other Description | prosalusin|salusin-beta|torsin-2A|torsin-related protein 1 |
Swissprots | Q8NAN5 Q5JU69 A4FU13 Q96SL7 Q3ZCN9 A4FU12 Q8N2E6 Q66K87 Q3ZCP0 Q6UXW6 Q5JU68 |
Accessions | CAI72173 CAI93200 EAW87690 EAW87691 EAW87692 EAW87693 EAW87694 Q5JU69 Q8N2E6 AK027677 BAB55288 AK055034 AK075520 BAC11667 AK092388 AY358180 AAQ88547 BC022985 BC062340 AAH62340 BC080527 AAH80527 BC100907 AAI00908 BC100908 AAI00909 BC100909 AAI00910 BC100910 AAI00911 BC156122 AAI56123 BC156918 AAI56919 BC160144 AAI60144 BF115698 BM695589 BM772287 CN263138 DA430836 DB168410 XM_011518553 XP_011516855 XM_011518554 XP_011516856 XM_011518555 XP_011516857 NM_001085347 NP_001078816 NM_001134430 NP_001127902 NM_001134431 NP_001127903 NM_001252018 NP_001238947 NM_001252021 NP_001238950 NM_001252023 NP_001238952 NM_130459 NP_569726 |
Function | Salusins -alpha and -beta may be endocrine and/or paracrine factors able to increase intracellular calcium concentrations and induce cell mitogenesis. Salusins may also be potent hypotensive peptides. {ECO:0000269|PubMed:12910263}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:12910263}. |
Tissue Specificity | Isoform 4 is ubiquitously expressed, with high level in vascular endothelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:12910263}. |
Torsin2A CRISPR/Cas9 KO Plasmid (h) - sc-412000 from Santa Cruz Biotechnology
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Torsin2A HDR Plasmid (h) - sc-412000-HDR from Santa Cruz Biotechnology
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Torsin2A Double Nickase Plasmid (h) - sc-412000-NIC from Santa Cruz Biotechnology
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Torsin2A Double Nickase Plasmid (h2) - sc-412000-NIC-2 from Santa Cruz Biotechnology
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Torsin2A CRISPR Activation Plasmid (h) - sc-412000-ACT from Santa Cruz Biotechnology
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Torsin2A CRISPR Activation Plasmid (h2) - sc-412000-ACT-2 from Santa Cruz Biotechnology
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Torsin2A Lentiviral Activation Particles (h) - sc-412000-LAC from Santa Cruz Biotechnology
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Torsin2A Lentiviral Activation Particles (h2) - sc-412000-LAC-2 from Santa Cruz Biotechnology
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Torsin2A siRNA (h) - sc-92871 from Santa Cruz Biotechnology
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Torsin2A shRNA Plasmid (h) - sc-92871-SH from Santa Cruz Biotechnology
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Torsin2A shRNA (h) Lentiviral Particles - sc-92871-V from Santa Cruz Biotechnology
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Torsin 2A RNAi - H00027433-R02 from Novus Biologicals
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Torsin 2A RNAi - H00027433-R01 from Novus Biologicals
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MISSION® esiRNA - EHU157581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21836 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21836 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12712 from Sigma-Aldrich
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TOR2A siRNA (Human) - CRH9104 from Cohesion Biosciences
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TOR2A siRNA (Human) - CRH9105 from Cohesion Biosciences
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TOR2A - MBS8237369 from MyBioSource
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TOR2A - MBS8228013 from MyBioSource
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shRNA set against Human Tor2a (NM_130459.3) - SHH432980 from Creative biogene
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TOR2A shRNA Plasmid (Human) - CHH9104 from Cohesion Biosciences
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TOR2A shRNA Plasmid (Human) - CHH9105 from Cohesion Biosciences
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TOR2A miRNA 3'UTR clone - MiUTR3H-09696 from Creative biogene
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