Gene Symbol | TNFRSF19 |
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Entrez Gene | 55504 |
Alt Symbol | TAJ, TAJ-alpha, TRADE, TROY |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 19 |
Other Description | toxicity and JNK inducer|tumor necrosis factor receptor superfamily member 19 |
Swissprots | Q9NZV2 Q9BY00 Q9BXZ9 A8KA26 Q9NS68 B4E2I6 B1AM41 B1AM40 A8KA09 |
Accessions | CAD88147 EAX08325 EAX08326 EAX08327 Q9NS68 AB040434 BAB03269 AF086276 AF167555 AAF71828 AF246998 AAK28395 AF246999 AAK28396 AK292874 BAF85563 AK292891 BAF85580 AK304290 BAG65148 AY358888 AAQ89247 BC035796 BC047321 AAH47321 BF968836 BF971156 BG674480 BI494770 BM801444 CA437886 DA192370 DB223760 XM_005266445 XP_005266502 XM_005266446 XP_005266503 XM_011535146 XP_011533448 NM_001204458 NP_001191387 NM_001204459 NP_001191388 NM_018647 NP_061117 NM_148957 NP_683760 |
Function | Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes. |
Top Pathways | Cytokine-cytokine receptor interaction |
TROY CRISPR/Cas9 KO Plasmid (h) - sc-418150 from Santa Cruz Biotechnology
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TROY HDR Plasmid (h) - sc-418150-HDR from Santa Cruz Biotechnology
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TROY Double Nickase Plasmid (h) - sc-418150-NIC from Santa Cruz Biotechnology
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TROY Double Nickase Plasmid (h2) - sc-418150-NIC-2 from Santa Cruz Biotechnology
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TROY CRISPR Activation Plasmid (h) - sc-418150-ACT from Santa Cruz Biotechnology
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TROY CRISPR Activation Plasmid (h2) - sc-418150-ACT-2 from Santa Cruz Biotechnology
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TROY Lentiviral Activation Particles (h) - sc-418150-LAC from Santa Cruz Biotechnology
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TROY Lentiviral Activation Particles (h2) - sc-418150-LAC-2 from Santa Cruz Biotechnology
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TROY siRNA (h) - sc-40247 from Santa Cruz Biotechnology
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TROY shRNA Plasmid (h) - sc-40247-SH from Santa Cruz Biotechnology
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TROY shRNA (h) Lentiviral Particles - sc-40247-V from Santa Cruz Biotechnology
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TROY/TNFRSF19 RNAi - H00055504-R03 from Novus Biologicals
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TROY/TNFRSF19 RNAi - H00055504-R04 from Novus Biologicals
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MISSION® esiRNA - EHU151421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21750 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21750 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00614 from Sigma-Aldrich
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TNFRSF19 siRNA (Human) - CRJ0713 from Cohesion Biosciences
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TNFRSF19 - MBS8218214 from MyBioSource
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shRNA set against Human TNFRSF19 (NM_018647.3) - SHH431968 from Creative biogene
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Human TNFRSF19 siRNA - orb271214 from Biorbyt
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TNFRSF19 shRNA Plasmid (Human) - CHJ0713 from Cohesion Biosciences
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TNFRSF19 miRNA 3'UTR clone - MiUTR3H-08232 from Creative biogene
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