Gene Symbol |
CSRP2
|
Entrez Gene |
1466
|
Alt Symbol |
CRP2, LMO5, SmLIM
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cysteine and glycine-rich protein 2
|
Other Description |
LIM domain only 5, smooth muscle|LIM domain only protein 5|LMO-5|cysteine-rich protein 2|smooth muscle cell LIM protein
|
Swissprots |
Q16527 Q93030
|
Accessions |
AAC51755 EAW97336 EAW97337 Q16527 AB209321 BAD92558 AY349166 BC000992 AAH00992 BT019913 AAV38716 BX461295 CN408330 DQ890975 ABM81901 DQ894149 ABM85075 U46006 AAC27344 U57646 AAC51753 XM_011537977 XP_011536279 NM_001300965 NP_001287894 NM_001321 NP_001312
|
Function |
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in the aorta, but not in heart and skeletal muscle.
|