| Gene Symbol |
CD300LB
|
| Entrez Gene |
124599
|
| Alt Symbol |
CD300b, CLM-7, CLM7, CMRF35-A2, IREM-3, IREM3, TREM-5, TREM5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD300 molecule-like family member b
|
| Other Description |
CD300 antigen like family member B|CMRF35-like molecule 7|immune receptor expressed on myeloid cells 3|leukocyte mono-Ig-like receptor 5|triggering receptor expressed on myeloid cells 5
|
| Swissprots |
Q8N6D1 Q1EG73 Q8IX40 A8K4G0
|
| Accessions |
A8K4G0 EAW89169 EAW89170 AF427618 AAN86133 AK290925 BAF83614 AK298665 BAG60833 AY359025 AAQ89384 AY646929 AAV69612 BC028091 AAH28091 DA673717 DQ893585 ABM84511 DQ896833 ABM87832 XM_005257027 XP_005257084 NM_174892 NP_777552
|
| Function |
Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. {ECO:0000269|PubMed:16920917, ECO:0000269|PubMed:17928527}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed exclusively in myeloid lineages. {ECO:0000269|PubMed:16920917}.
|
![Western Blot: CD300LB Overexpression Lysate (Adult Normal) [NBP2-05072] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CD300LB.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4164_CD300LB%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05072-img0001.jpg)