Gene Symbol | ARHGEF10L |
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Entrez Gene | 55160 |
Alt Symbol | GrinchGEF |
Species | Human |
Gene Type | protein-coding |
Description | Rho guanine nucleotide exchange factor (GEF) 10-like |
Other Description | rho guanine nucleotide exchange factor 10-like protein |
Swissprots | Q6P0L7 Q8NAV5 Q3YFJ4 Q9HCE6 Q66K51 Q5VXI5 B7ZKS1 Q9NVT3 Q5VXI6 Q17RW1 |
Accessions | EAW94840 EAW94841 EAW94842 EAW94843 EAW94844 Q9HCE6 AB046846 BAB13452 AK001383 BAA91663 AK092020 BAC03792 AK123471 AK126877 BAG54386 AK129606 AK129959 AK300174 BAG61954 AK300264 BAG62025 AK311076 AW455769 BC003073 BC029928 BC065561 AAH65561 BC080596 AAH80596 BC111058 BC117171 AAI17172 BC143347 AAI43348 DQ139833 AAZ73162 HQ258640 ADR83391 XM_005245923 XP_005245980 XM_005245925 XP_005245982 XM_005245927 XP_005245984 XM_005245929 XP_005245986 XM_006710728 XP_006710791 XM_006710729 XP_006710792 XM_006710731 XP_006710794 XM_011541691 XP_011539993 XM_011541692 XP_011539994 XM_011541693 XP_011539995 XM_011541694 XP_011539996 XM_011541695 XP_011539997 XM_011541696 XP_011539998 XR_946686 XR_946687 XR_946688 XR_946689 XR_946690 XR_946691 NM_001011722 NP_001011722 NM_018125 NP_060595 |
Function | Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. {ECO:0000269|PubMed:16112081}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16112081}. |
Tissue Specificity | Detected in heart, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:16112081}. |
ARHGEF10L CRISPR/Cas9 KO Plasmid (h) - sc-412465 from Santa Cruz Biotechnology
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ARHGEF10L HDR Plasmid (h) - sc-412465-HDR from Santa Cruz Biotechnology
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ARHGEF10L Double Nickase Plasmid (h) - sc-412465-NIC from Santa Cruz Biotechnology
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ARHGEF10L Double Nickase Plasmid (h2) - sc-412465-NIC-2 from Santa Cruz Biotechnology
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ARHGEF10L CRISPR Activation Plasmid (h) - sc-412465-ACT from Santa Cruz Biotechnology
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ARHGEF10L CRISPR Activation Plasmid (h2) - sc-412465-ACT-2 from Santa Cruz Biotechnology
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ARHGEF10L Lentiviral Activation Particles (h) - sc-412465-LAC from Santa Cruz Biotechnology
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ARHGEF10L Lentiviral Activation Particles (h2) - sc-412465-LAC-2 from Santa Cruz Biotechnology
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ARHGEF10L siRNA (h) - sc-88567 from Santa Cruz Biotechnology
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ARHGEF10L shRNA Plasmid (h) - sc-88567-SH from Santa Cruz Biotechnology
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ARHGEF10L shRNA (h) Lentiviral Particles - sc-88567-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU091371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3443 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3443 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04941 from Sigma-Aldrich
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ARHGEF10L siRNA (Human) - CRJ0515 from Cohesion Biosciences
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ARHGEF10L - MBS8205142 from MyBioSource
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shRNA set against Human ARHGEF10L (NM_018125.3) - SHH239694 from Creative biogene
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shRNA set against Human ARHGEF10L(NM_018125.3) - SHG070759 from Creative biogene
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shRNA set against Human ARHGEF10L(NM_001011722.2) - SHG070777 from Creative biogene
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Human ARHGEF10L siRNA - orb271016 from Biorbyt
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ARHGEF10L shRNA Plasmid (Human) - CHJ0515 from Cohesion Biosciences
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ARHGEF10L miRNA 3'UTR clone - MiUTR1H-00539 from Creative biogene
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ARHGEF10L miRNA 3'UTR clone - MiUTR1H-00540 from Creative biogene
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