Gene Symbol | PCBP1 |
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Entrez Gene | 5093 |
Alt Symbol | HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X |
Species | Human |
Gene Type | protein-coding |
Description | poly(rC) binding protein 1 |
Other Description | alpha-CP1|epididymis secretory protein Li 85|heterogeneous nuclear ribonucleoprotein E1|heterogenous nuclear ribonucleoprotein E1|heterogenous nuclear ribonucleoprotein X|nucleic acid-binding protein SUB2.3|poly(rC)-binding protein 1 |
Swissprots | Q15365 Q13157 Q14975 |
Accessions | AAX93191 EAW99834 Q15365 AK130439 AK314225 BAG36897 BC039742 AAH39742 BM794597 FJ224329 ACI46021 HQ447984 ADQ32466 U24223 AAA91317 X78137 CAA55016 Z29505 CAA82631 NM_006196 NP_006187 |
Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. |
Subcellular Location | Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm. |
Tissue Specificity | Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. |
Top Pathways | Spliceosome |
SignalSilence ® hnRNP E1 siRNA II - 7987 from Cell Signaling Technology
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SignalSilence ® hnRNP E1 siRNA I - 7798 from Cell Signaling Technology
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hnRNP E1 CRISPR/Cas9 KO Plasmid (h) - sc-401557 from Santa Cruz Biotechnology
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hnRNP E1 HDR Plasmid (h) - sc-401557-HDR from Santa Cruz Biotechnology
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hnRNP E1 Double Nickase Plasmid (h) - sc-401557-NIC from Santa Cruz Biotechnology
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hnRNP E1 Double Nickase Plasmid (h2) - sc-401557-NIC-2 from Santa Cruz Biotechnology
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hnRNP E1 CRISPR Activation Plasmid (h) - sc-401557-ACT from Santa Cruz Biotechnology
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hnRNP E1 CRISPR Activation Plasmid (h2) - sc-401557-ACT-2 from Santa Cruz Biotechnology
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hnRNP E1 Lentiviral Activation Particles (h) - sc-401557-LAC from Santa Cruz Biotechnology
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hnRNP E1 Lentiviral Activation Particles (h2) - sc-401557-LAC-2 from Santa Cruz Biotechnology
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hnRNP E1 siRNA (h) - sc-38268 from Santa Cruz Biotechnology
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hnRNP E1 shRNA Plasmid (h) - sc-38268-SH from Santa Cruz Biotechnology
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hnRNP E1 shRNA (h) Lentiviral Particles - sc-38268-V from Santa Cruz Biotechnology
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hnRNP E1/E2 siRNA (h) - sc-43843 from Santa Cruz Biotechnology
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hnRNP E1/E2 shRNA Plasmid (h) - sc-43843-SH from Santa Cruz Biotechnology
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hnRNP E1/E2 shRNA (h) Lentiviral Particles - sc-43843-V from Santa Cruz Biotechnology
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PCBP1 RNAi - H00005093-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16392 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16392 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03749 from Sigma-Aldrich
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PCBP1 siRNA (Human) - CRH3387 from Cohesion Biosciences
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shRNA set against Human PCBP1 (NM_006196.3) - SHH371376 from Creative biogene
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PCBP1 shRNA Plasmid (Human) - CHH3387 from Cohesion Biosciences
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PCBP1 miRNA 3'UTR clone - MiUTR3H-03948 from Creative biogene
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