| Gene Symbol |
SETD6
|
| Entrez Gene |
79918
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SET domain containing 6
|
| Other Description |
N-lysine methyltransferase SETD6|SET domain-containing protein 6
|
| Swissprots |
B5ME38 Q9H787 A8K380 Q8TBK2
|
| Accessions |
EAW82980 EAW82981 Q8TBK2 AK024801 BAB15011 AK127136 BAC86845 AK290495 BAF83184 AK297288 BAG59758 AK304822 BAG65570 AK309468 BC022451 AAH22451 BC110433 BP338820 DA074170 GD152628 XM_011523336 XP_011521638 XM_011523337 XP_011521639 XR_243428 XR_243429 XR_933436 XR_933437 NM_001160305 NP_001153777 NM_024860 NP_079136
|
| Function |
Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. {ECO:0000269|PubMed:21131967}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21131967}.
|
![Western Blot: SETD6 Overexpression Lysate (Adult Normal) [NBP2-06275] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SETD6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10245_SETD6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06275-img0001.jpg)