YCS4

Gene Symbol YCS4
Entrez Gene 850977
Alt Symbol LOC7
Species Yeast
Gene Type protein-coding
Description Ycs4p
Other Description -
Swissprots D6VYR9 Q06156
Accessions DAA09585 Q06156 NM_001182159 NP_013374
Function Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase. {ECO:0000269|PubMed:11854418}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11854418}. Chromosome {ECO:0000269|PubMed:11854418}. Note=Nuclear throughout the cell cycle. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. At anaphase, it is enriched at rDNA. Dissociation from chromosomes is observed in late telophase.
Top Pathways Cell cycle - yeast