Gene Symbol | YCS4 |
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Entrez Gene | 850977 |
Alt Symbol | LOC7 |
Species | Yeast |
Gene Type | protein-coding |
Description | Ycs4p |
Other Description | - |
Swissprots | D6VYR9 Q06156 |
Accessions | DAA09585 Q06156 NM_001182159 NP_013374 |
Function | Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase. {ECO:0000269|PubMed:11854418}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11854418}. Chromosome {ECO:0000269|PubMed:11854418}. Note=Nuclear throughout the cell cycle. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. At anaphase, it is enriched at rDNA. Dissociation from chromosomes is observed in late telophase. |
Top Pathways | Cell cycle - yeast |
Recombinant Saccharomyces cerevisiae Condensin complex subunit 1(YCS4) ,partial - CSB-YP015514SVG CSB-EP015514SVG CSB-BP015514SVG CSB-MP015514SVG from Cusabio
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Condensin complex subunit 1 (YCS4), partial, Recombinant Protein - MBS1057662 from MyBioSource
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