Gene Symbol | ALS2 |
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Entrez Gene | 57679 |
Alt Symbol | ALS2CR6, ALSJ, IAHSP, PLSJ |
Species | Human |
Gene Type | protein-coding |
Description | amyotrophic lateral sclerosis 2 (juvenile) |
Other Description | alsin|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein|amyotrophic lateral sclerosis 2 protein |
Swissprots | Q53TV2 Q9HCK9 Q8N1E0 Q53TT1 Q96PC4 Q96Q42 Q9H973 Q96Q41 |
Accessions | AAX93181 AAY15058 EAW70291 EAW70292 EAW70293 Q96Q42 AB046783 BAB13389 AB053305 BAB69014 AB053306 BAB69015 AF391100 AAL14103 AK023024 BAB14362 AK056413 BAG51702 AK291029 BAF83718 BC029174 AAH29174 BC071576 AAH71576 BM560426 BM978733 BP348546 BU623061 XM_005246709 XP_005246766 XM_006712654 XP_006712717 XM_006712655 XP_006712718 XM_011511530 XP_011509832 XM_011511531 XP_011509833 XR_922974 NM_001135745 NP_001129217 NM_020919 NP_065970 |
Function | May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity). {ECO:0000250}. |
Top Pathways | Amyotrophic lateral sclerosis (ALS) |
Alsin CRISPR/Cas9 KO Plasmid (h) - sc-407087 from Santa Cruz Biotechnology
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Alsin HDR Plasmid (h) - sc-407087-HDR from Santa Cruz Biotechnology
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Alsin Double Nickase Plasmid (h) - sc-407087-NIC from Santa Cruz Biotechnology
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Alsin Double Nickase Plasmid (h2) - sc-407087-NIC-2 from Santa Cruz Biotechnology
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Alsin CRISPR Activation Plasmid (h) - sc-407087-ACT from Santa Cruz Biotechnology
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Alsin CRISPR Activation Plasmid (h2) - sc-407087-ACT-2 from Santa Cruz Biotechnology
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Alsin Lentiviral Activation Particles (h) - sc-407087-LAC from Santa Cruz Biotechnology
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Alsin Lentiviral Activation Particles (h2) - sc-407087-LAC-2 from Santa Cruz Biotechnology
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Alsin siRNA (h) - sc-60158 from Santa Cruz Biotechnology
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Alsin shRNA Plasmid (h) - sc-60158-SH from Santa Cruz Biotechnology
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Alsin shRNA (h) Lentiviral Particles - sc-60158-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3089 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3089 from Sigma-Aldrich
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ALS2 siRNA (Human) - CRJ1626 from Cohesion Biosciences
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Als2 RNAi - H00057679-R01 from Novus Biologicals
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ALS2 - MBS8200883 from MyBioSource
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shRNA set against Human ALS2 (NM_020919.3) - SHH235510 from Creative biogene
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shRNA set against Human ALS2(NM_020919.3) - SHG054685 from Creative biogene
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ALS2 shRNA Plasmid (Human) - CHJ1626 from Cohesion Biosciences
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ALS2 miRNA 3'UTR clone - MiUTR3H-08389 from Creative biogene
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ALS2 miRNA 3'UTR clone - MiUTR3H-08390 from Creative biogene
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