Gene Symbol | SFTPA2 |
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Entrez Gene | 729238 |
Alt Symbol | COLEC5, PSAP, PSP-A, PSPA, SFTP1, SFTPA2B, SP-A, SPA2, SPAII |
Species | Human |
Gene Type | protein-coding |
Description | surfactant protein A2 |
Other Description | 35 kDa pulmonary surfactant-associated protein|alveolar proteinosis protein|collectin 5|pulmonary surfactant-associated protein A2|surfactant, pulmonary-associated protein A2A |
Swissprots | C9J9I7 A4QPA7 Q8IWL1 E3VLC9 E3VLC8 B2RXK9 Q14DV3 E3VLC6 Q5RIR9 P07714 E3VLC7 Q5RIR8 B2RXI6 |
Accessions | Q8IWL1 AK225599 AK298041 BAH12710 AK298074 BAH12720 AK298114 BAH12725 AK313179 BAG35996 AK316192 BAH14563 BC111571 AAI11572 BC139727 AAI39728 BC157866 AAI57867 BC157890 AAI57891 HQ021421 ADO27664 HQ021422 ADO27665 HQ021423 ADO27666 HQ021424 ADO27667 HQ021425 ADO27668 HQ021426 ADO27669 HQ021427 ADO27670 HQ021428 ADO27671 HQ021429 ADO27672 HQ021430 ADO27673 HQ021431 ADO27674 HQ021432 ADO27675 K03475 AAA36520 XM_005270128 XP_005270185 XM_005270131 XP_005270188 XM_005270132 XP_005270189 XM_011540124 XP_011538426 XM_011540125 XP_011538427 NM_001098668 NP_001092138 |
Function | In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
Top Pathways | Phagosome, Pertussis |
SP-A CRISPR/Cas9 KO Plasmid (h) - sc-416186 from Santa Cruz Biotechnology
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SP-A HDR Plasmid (h) - sc-416186-HDR from Santa Cruz Biotechnology
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SP-A Double Nickase Plasmid (h) - sc-416186-NIC from Santa Cruz Biotechnology
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SP-A Double Nickase Plasmid (h2) - sc-416186-NIC-2 from Santa Cruz Biotechnology
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SP-A CRISPR Activation Plasmid (h) - sc-416186-ACT from Santa Cruz Biotechnology
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SP-A CRISPR Activation Plasmid (h2) - sc-416186-ACT-2 from Santa Cruz Biotechnology
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SP-A Lentiviral Activation Particles (h) - sc-416186-LAC from Santa Cruz Biotechnology
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SP-A Lentiviral Activation Particles (h2) - sc-416186-LAC-2 from Santa Cruz Biotechnology
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PSAP RNAi - H00005660-R02 from Novus Biologicals
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PSAP RNAi - H00005660-R03 from Novus Biologicals
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PSAP RNAi - H00005660-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN19209 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19209 from Sigma-Aldrich
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SFTPA2 siRNA (Human) - CRJ8710 from Cohesion Biosciences
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SFTPA2 - MBS8204568 from MyBioSource
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shRNA set against Human SFTPA2 (NM_001098668.2) - SHH406060 from Creative biogene
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Human SFTPA2 siRNA - orb279211 from Biorbyt
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SFTPA2 shRNA Plasmid (Human) - CHJ8710 from Cohesion Biosciences
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SFTPA2 miRNA 3'UTR clone - MiUTR4H-TG07999 from Creative biogene
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